The human B1 bradykinin receptor exhibits high ligand-independent, constitutive activity. Roles of residues in the fourth intracellular and third transmembrane domains.
about
Overexpression of kinin B1 receptors induces hypertensive response to des-Arg9-bradykinin and susceptibility to inflammationDifferential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptorsA signal transduction pathway model prototype I: From agonist to cellular endpoint.Kinin-stimulated B1 receptor signaling depends on receptor endocytosis whereas B2 receptor signaling does not.Structure and signalling pathways of kinin receptors.Bradykinin receptors as a therapeutic target.Carboxypeptidase M is a positive allosteric modulator of the kinin B1 receptor.Soluble gC1qR is an autocrine signal that induces B1R expression on endothelial cells.New topics in bradykinin research.New concepts in pharmacological efficacy at 7TM receptors: IUPHAR review 2.HAE Pathophysiology and Underlying Mechanisms.Bradykinin regulates osteoblast differentiation by Akt/ERK/NFκB signaling axis.Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.Kinin receptor expression during Staphylococcus aureus infection.Pharmacological characterization of ligand-receptor interactions at the zebrafish bradykinin receptor.Control of conformational equilibria in the human B2 bradykinin receptor. Modeling of nonpeptidic ligand action and comparison to the rhodopsin structure.A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists.Kinin B1 receptors as a therapeutic target for inflammation.The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.The renin angiotensin system and the metabolic syndrome.Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genesMaking Sense of Pharmacology: Inverse Agonism and Functional Selectivity
P2860
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P2860
The human B1 bradykinin receptor exhibits high ligand-independent, constitutive activity. Roles of residues in the fourth intracellular and third transmembrane domains.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The human B1 bradykinin recept ...... d third transmembrane domains.
@ast
The human B1 bradykinin recept ...... d third transmembrane domains.
@en
type
label
The human B1 bradykinin recept ...... d third transmembrane domains.
@ast
The human B1 bradykinin recept ...... d third transmembrane domains.
@en
prefLabel
The human B1 bradykinin recept ...... d third transmembrane domains.
@ast
The human B1 bradykinin recept ...... d third transmembrane domains.
@en
P2093
P2860
P356
P1476
The human B1 bradykinin recept ...... d third transmembrane domains.
@en
P2093
P2860
P304
P356
10.1074/JBC.M007396200
P407
P577
2000-12-27T00:00:00Z