N-MYC regulates focal adhesion kinase expression in human neuroblastoma. - Wikidata - awgldk - TriplyDB

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

http://www.wikidata.org/entity/Q31814799

about

Cell Proliferation in Neuroblastoma Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis Network-based analysis of multivariate gene expression data.Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells.ATM is down-regulated by N-Myc-regulated microRNA-421.Didymin: an orally active citrus flavonoid for targeting neuroblastoma.Inhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell lines Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma.Requirement of PEA3 for transcriptional activation of FAK gene in tumor metastasis.Inhibition of FAK and VEGFR-3 binding decreases tumorigenicity in neuroblastoma.MYCN, neuroblastoma and focal adhesion kinase (FAK)Targeting focal adhesion kinase in neuroblastoma.Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival.Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma.Nanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated.FAK Inhibition Decreases Hepatoblastoma Survival Both In Vitro and In Vivo.FAK inhibition decreases cell invasion, migration and metastasis in MYCN amplified neuroblastoma Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms.Preclinical Evaluation of UAB30 in Pediatric Renal and Hepatic Malignancies FAK is a critical regulator of neuroblastoma liver metastasis.Cell survival signaling in neuroblastoma.A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth.SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells.Neuroblastoma and MYCN Inhibition of the focal adhesion kinase and vascular endothelial growth factor receptor-3 interaction leads to decreased survival in human neuroblastoma cell lines.FAK inhibition abrogates the malignant phenotype in aggressive pediatric renal tumors TGF-beta1 modulates focal adhesion kinase expression in rat intestinal epithelial IEC-6 cells via stimulatory and inhibitory Smad binding elements.Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.

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P2860

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

http://www.wikidata.org/entity/Q31814799

description

2007 nî lūn-bûn

@nan

2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

@ast

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

@en

type

label

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

@ast

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

@en

prefLabel

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

@ast

N-MYC regulates focal adhesion kinase expression in human neuroblastoma.

@en

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P1433

Journal of Biological Chemistry

P1476

N-MYC regulates focal adhesion kinase expression in human neuroblastoma

@en

P2093

Abhilasha Nagaram

http://www.w3.org/2001/XMLSchema#string

Angelica Trujillo

http://www.w3.org/2001/XMLSchema#string

Elena V Kurenova

http://www.w3.org/2001/XMLSchema#string

Jennifer Vella

http://www.w3.org/2001/XMLSchema#string

Richard Finch

http://www.w3.org/2001/XMLSchema#string

Vita M Golubovskaya

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William G Cance

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Xiaojie Ma

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P2860

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Nucleotide sequence of the human N-myc gene

FAK regulates biological processes important for the pathogenesis of cancer

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors

Control of adhesion-dependent cell survival by focal adhesion kinase

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase.

Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoter

The basic region/helix-loop-helix/leucine zipper domain of Myc proto-oncoproteins: function and regulation.

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12503-12516

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scholarly article

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10.1074/JBC.M701450200

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P433

17

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P478

282

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P50

Elizabeth A. Beierle

P577

2007-02-27T00:00:00Z

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P698

17327229

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P921

positive regulation of transcription from RNA polymerase II promoter

MYCN proto-oncogene, bHLH transcription factor