Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis.
about
The mechanisms of UV mutagenesis.Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cellsSolar-UV-signature mutation prefers TCG to CCG: extrapolative consideration from UVA1-induced mutation spectra in mouse skin.Rotational position of a 5-methylcytosine-containing cyclobutane pyrimidine dimer in a nucleosome greatly affects its deamination rate.UV signature mutations.On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Frequency and features of TP53 mutation in 30 Chinese patients with sporadic basal cell carcinoma.Requirement of Rad18 protein for replication through DNA lesions in mouse and human cells.Into the eye of the storm: breast cancer's somatic mutation landscape points to DNA damage and repairRev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not DNA polymerase ζSignificance of CpG methylation for solar UV-induced mutagenesis and carcinogenesis in skin.Genetic factors associated with skin cancer in renal transplant patients.Mutagenicity of tamoxifen DNA adducts in human endometrial cells and in silico prediction of p53 mutation hotspots.In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure.Epigenetics and dermatological disease.Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells.Novel vitamin D compounds and skin cancer prevention.Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis.UVB irradiation does not directly induce detectable changes of DNA methylation in human keratinocytes.Different types of DNA damage play different roles in the etiology of sunlight-induced melanomaUltraviolet Radiation in Wound Care: Sterilization and StimulationAcceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots.S-(2-chloroethyl)glutathione-generated p53 mutation spectra are influenced by differential repair rates more than sites of initial dna damage.Investigation of the mechanisms of photo-induced formation of cyclobutane dimers of cytosine and 2,4-diaminopyrimidine.UVA-induced epigenetic regulation of P16(INK4a) in human epidermal keratinocytes and skin tumor derived cells.
P2860
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P2860
Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Similarities in sunlight-induc ...... idues in solar UV mutagenesis.
@ast
Similarities in sunlight-induc ...... idues in solar UV mutagenesis.
@en
type
label
Similarities in sunlight-induc ...... idues in solar UV mutagenesis.
@ast
Similarities in sunlight-induc ...... idues in solar UV mutagenesis.
@en
prefLabel
Similarities in sunlight-induc ...... idues in solar UV mutagenesis.
@ast
Similarities in sunlight-induc ...... idues in solar UV mutagenesis.
@en
P356
P1476
Similarities in sunlight-induc ...... idues in solar UV mutagenesis.
@en
P2093
P304
P356
10.1006/JMBI.2000.4322
P577
2001-01-01T00:00:00Z