Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond.
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Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancerProphylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapyPoly(amido amine) dendrimers as absorption enhancers for oral delivery of camptothecin.CK2-mediated hyperphosphorylation of topoisomerase I targets serine 506, enhances topoisomerase I-DNA binding, and increases cellular camptothecin sensitivity.Protein kinase CK2 is a central regulator of topoisomerase I hyperphosphorylation and camptothecin sensitivity in cancer cell linesIterative and prolonged remission in metastatic breast cancer using pegylated irinotecan: a case report.IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models.Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer ActivityIrinotecan (CPT-11) chemotherapy alters intestinal microbiota in tumour bearing rats.Docetaxel in ovarian cancer.1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane potentiates in vitro and in vivo antitumor effects of irinotecan on human colorectal cancer cellsInvestigation into the Efficacy of Val-SN-38, a Valine-Ester Prodrug of the Anti-Cancer Agent SN-38.No topoisomerase I alteration in a neuroblastoma model with in vivo acquired resistance to irinotecanPhase I and pharmacokinetic study of mitomycin C and celecoxib as potential modulators of tumor resistance to irinotecan in patients with solid malignancies.High-grade neuroendocrine carcinoma of the colon, long-term survival in advanced disease.Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.Ginger augmented chemotherapy: A novel multitarget nontoxic approach for cancer management.Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment.Synthesis, characterization, and biological studies of emissive rhenium-glutamine conjugates.Resveratrol derivatives as a pharmacological tool.G3.5 PAMAM dendrimers enhance transepithelial transport of SN38 while minimizing gastrointestinal toxicity.Evaluation of [18F]Fluorothymidine as a Biomarker for Early Therapy Response in a Mouse Model of Colorectal Cancer.Simvastatin enhances irinotecan-induced apoptosis in human non-small cell lung cancer cells by inhibition of proteasome activity.Synthesis and evaluation of a molecularly imprinted polymer for selective solid-phase extraction of irinotecan from human serum samples.Colony-stimulating factor use and impact on febrile neutropenia among patients with newly diagnosed breast, colorectal, or non-small cell lung cancer who were receiving chemotherapy.Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.Anti-HSV activity of camptothecin analogues.Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38.Biophysical and molecular docking insight into interaction mechanism and thermal stability of human serum albumin isoforms with a semi-synthetic water-soluble camptothecin analog irinotecan hydrochloride.Solubility-Improved 10-O-Substituted SN-38 Derivatives with Antitumor Activity.Evaluation of [18F]CP18 as a Substrate-Based Apoptosis Imaging Agent for the Assessment of Early Treatment Response in Oncology.Topoisomerases as anticancer targets.
P2860
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P2860
Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Irinotecan (CPT-11): recent de ...... -colorectal cancer and beyond.
@ast
Irinotecan (CPT-11): recent de ...... -colorectal cancer and beyond.
@en
type
label
Irinotecan (CPT-11): recent de ...... -colorectal cancer and beyond.
@ast
Irinotecan (CPT-11): recent de ...... -colorectal cancer and beyond.
@en
prefLabel
Irinotecan (CPT-11): recent de ...... -colorectal cancer and beyond.
@ast
Irinotecan (CPT-11): recent de ...... -colorectal cancer and beyond.
@en
P1433
P1476
Irinotecan (CPT-11): recent de ...... -colorectal cancer and beyond.
@en
P2093
M L Rothenberg
P356
10.1634/THEONCOLOGIST.6-1-66
P577
2001-01-01T00:00:00Z