Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

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Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics.

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Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

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Effect of Cellular Location of ...... olysis and Anticancer Activity

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Effect of Cellular Location of ...... olysis and Anticancer Activity

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Effect of Cellular Location of ...... olysis and Anticancer Activity

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Effect of Cellular Location of ...... olysis and Anticancer Activity

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Bing-Mae Chen

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Hsuan-Pei Lin

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Ping-Ting Huang

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Steve R Roffler

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Yuan-Ting Hsieh

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P2860

Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver

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Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs

ATP-Dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P

Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond.

Irinotecan plus fluorouracil/leucovorin for metastatic colorectal cancer: a new survival standard.

Phase II study of nedaplatin and irinotecan with concurrent thoracic radiotherapy in patients with locally advanced non-small-cell lung cancer.

Directed evolution of a lysosomal enzyme with enhanced activity at neutral pH by mammalian cell-surface display.

Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.

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scholarly article

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10.1371/JOURNAL.PONE.0141088

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Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

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P2860

P2860

Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

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P5875

P698

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932