TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway.
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Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilizationMutational activation of the MAP3K8 protooncogene in lung cancerChemoprotection by phenolic antioxidantsCytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanismsABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stabilityThe tyrosine kinase Syk regulates TPL2 activation signalsMLK3 is required for mitogen activation of B-Raf, ERK and cell proliferationNF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activityCARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomesDissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine releaseProstaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activationAkt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription.Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAsThe kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAsLoss of tumor progression locus 2 (tpl2) enhances tumorigenesis and inflammation in two-stage skin carcinogenesisMicrobe sensing, positive feedback loops, and the pathogenesis of inflammatory diseasesThe COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activityTpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondiiInterleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinaseNF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responsesPhosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZThe oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NF-kappaB signaling downstream of TRAF2Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cellsExpression of the Tpl2/Cot oncogene in human T-cell neoplasiasMnk kinase pathway: Cellular functions and biological outcomesThe TLR and IL-1 signalling network at a glanceTumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancerHemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages.Tumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8+ T Cell Responses and Protects against Influenza VirusImplication of inflammatory signaling pathways in obesity-induced insulin resistanceNF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic ImplicationsIdentification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signalingTLR signalingRegulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinaseMAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomasBikunin inhibits lipopolysaccharide-induced tumor necrosis factor alpha induction in macrophagesThe protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs)Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways.ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responsesPharmacological Inactivation of Src Family Kinases Inhibits LPS-Induced TNF-α Production in PBMC of Patients with Behçet's Disease
P2860
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P2860
TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
TNF-alpha induction by LPS is ...... a Tpl2/ERK-dependent pathway.
@ast
TNF-alpha induction by LPS is ...... a Tpl2/ERK-dependent pathway.
@en
type
label
TNF-alpha induction by LPS is ...... a Tpl2/ERK-dependent pathway.
@ast
TNF-alpha induction by LPS is ...... a Tpl2/ERK-dependent pathway.
@en
prefLabel
TNF-alpha induction by LPS is ...... a Tpl2/ERK-dependent pathway.
@ast
TNF-alpha induction by LPS is ...... a Tpl2/ERK-dependent pathway.
@en
P2093
P1433
P1476
TNF-alpha induction by LPS is ...... a Tpl2/ERK-dependent pathway.
@en
P2093
Copeland NG
Dumitru CD
Jenkins NA
Kontoyiannis D
Patriotis C
Stamatakis K
Tsatsanis C
P304
P356
10.1016/S0092-8674(00)00210-5
P407
P577
2000-12-01T00:00:00Z