Cytochrome c oxidase deficient cells accumulate in the hippocampus and choroid plexus with age.
about
Age-associated mosaic respiratory chain deficiency causes trans-neuronal degenerationImpaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivoThe role of mitochondrial DNA mutations in mammalian agingDefects in multiple complexes of the respiratory chain are present in ageing human colonic crypts.Somatic mitochondrial DNA deletions accumulate to high levels in aging human extraocular muscles.Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice.High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratioTime of our lives. What controls the length of life?Comparison of mitochondrial mutation spectra in ageing human colonic epithelium and disease: absence of evidence for purifying selection in somatic mitochondrial DNA point mutations.Human stem cell aging: do mitochondrial DNA mutations have a causal role?Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type miceProgressive parkinsonism in mice with respiratory-chain-deficient dopamine neuronsVisualization of mitochondrial respiratory function using cytochrome c oxidase/succinate dehydrogenase (COX/SDH) double-labeling histochemistry.The choroid plexus: function, pathology and therapeutic potential of its transplantation.Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis.The ageing mitochondrial genomeA role of the choroid plexus in transplantation therapy.The role of mitochondria in agingMitochondrial DNA mutations and aging.Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis.Mitochondrial mutations: newly discovered players in neuronal degeneration.Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets.The effect of aging on brain barriers and the consequences for Alzheimer's disease development.Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases.The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations.Myopathology of Adult and Paediatric Mitochondrial Diseases.Detection and quantification of mitochondrial DNA deletions in individual cells by real-time PCR.Quantification of mitochondrial DNA mutation loadThe role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease.Aging reduces the neuroprotective capacity, VEGF secretion, and metabolic activity of rat choroid plexus epithelial cells.The Mitochondrial Basis of Aging and Age-Related Disorders.Role of Sex Hormones on Brain Mitochondrial Function, with Special Reference to Aging and Neurodegenerative Diseases.Molecular neuropathology of MELAS: level of heteroplasmy in individual neurones and evidence of extensive vascular involvement.Choroid plexus and ageing in rats: a morphometric and ultrastructural study.Roles of Mitochondrial DNA Mutations in Stem Cell Ageing.
P2860
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P2860
Cytochrome c oxidase deficient cells accumulate in the hippocampus and choroid plexus with age.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Cytochrome c oxidase deficient ...... s and choroid plexus with age.
@ast
Cytochrome c oxidase deficient ...... s and choroid plexus with age.
@en
type
label
Cytochrome c oxidase deficient ...... s and choroid plexus with age.
@ast
Cytochrome c oxidase deficient ...... s and choroid plexus with age.
@en
prefLabel
Cytochrome c oxidase deficient ...... s and choroid plexus with age.
@ast
Cytochrome c oxidase deficient ...... s and choroid plexus with age.
@en
P2093
P1476
Cytochrome c oxidase deficient ...... s and choroid plexus with age.
@en
P2093
Blakely EL
Borthwick GM
Cottrell DA
Johnson MA
Turnbull DM
P304
P356
10.1016/S0197-4580(00)00234-7
P577
2001-03-01T00:00:00Z