Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway.
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Role of Curcumin in Common Musculoskeletal Disorders: a Review of Current Laboratory, Translational, and Clinical Data.A dual role for oncostatin M signaling in the differentiation and death of mammary epithelial cells in vivo.LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model.Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines.IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway.Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis.Lessons from animal models of arthritis.Cardiotrophin-1 induces matrix metalloproteinase-1 in human aortic endothelial cellsOncostatin M inhibits myoblast differentiation and regulates muscle regeneration.Aberrant collagenase expression in chronic idiopathic myelofibrosis is related to the stage of disease but not to the JAK2 mutation status.Aging-related inflammation in osteoarthritis.p21 deficiency is susceptible to osteoarthritis through STAT3 phosphorylation.Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity.Synovial fibroblasts: key players in rheumatoid arthritis.Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you?Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytesDefining the roles of inflammatory and anabolic cytokines in cartilage metabolism.Inflammatory cytokines and the GH/IGF-I axis: novel actions on bone growth.Action mechanisms of complementary and alternative medicine therapies for rheumatoid arthritis.Molecular mechanisms of curcumin action: gene expression.Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?The potential for dietary factors to prevent or treat osteoarthritis.Curcumin and lung cancer--a review.Genomic view of IFN-alpha response in pre-autoimmune NZB/W and MRL/lpr mice.Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease.Blockade of recombinant human IL-6 by tocilizumab suppresses matrix metalloproteinase-9 production in the C28/I2 immortalized human chondrocyte cell line.Expression of nephronectin is inhibited by oncostatin M via both JAK/STAT and MAPK pathwaysMatrix metalloproteinase-13 expression in IL-1β-treated chondrocytes by activation of the p38 MAPK/c-Fos/AP-1 and JAK/STAT pathways.HGF synthesis in human lung fibroblasts is regulated by oncostatin M.MEK/ERK and signal transducer and activator of transcription signaling pathways modulate oncostatin M-stimulated CCL2 expression in human osteoblasts through a common transcription factor.Cytokine suppression of dopamine-beta-hydroxylase by extracellular signal-regulated kinase-dependent and -independent pathways.Borrelia burgdorferi-induced expression of matrix metalloproteinases from human chondrocytes requires mitogen-activated protein kinase and Janus kinase/signal transducer and activator of transcription signaling pathways.Inhibition of TAK1 and/or JAK can rescue impaired chondrogenic differentiation of human mesenchymal stem cells in osteoarthritis-like conditionsAdenoviral gene transfer of interleukin-1 in combination with oncostatin M induces significant joint damage in a murine model.The landscape of protein biomarkers proposed for periodontal disease: markers with functional meaning.Curcumin inhibits pro-inflammatory mediators and metalloproteinase-3 production by chondrocytes.Interleukin-1beta-induced extracellular matrix degradation and glycosaminoglycan release is inhibited by curcumin in an explant model of cartilage inflammation.Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factorInhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway.Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells.
P2860
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P2860
Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Oncostatin M-induced matrix me ...... kinase/STAT signaling pathway.
@ast
Oncostatin M-induced matrix me ...... kinase/STAT signaling pathway.
@en
type
label
Oncostatin M-induced matrix me ...... kinase/STAT signaling pathway.
@ast
Oncostatin M-induced matrix me ...... kinase/STAT signaling pathway.
@en
prefLabel
Oncostatin M-induced matrix me ...... kinase/STAT signaling pathway.
@ast
Oncostatin M-induced matrix me ...... kinase/STAT signaling pathway.
@en
P2093
P1476
Oncostatin M-induced matrix me ...... kinase/STAT signaling pathway.
@en
P2093
P304
P356
10.4049/JIMMUNOL.166.5.3491
P407
P577
2001-03-01T00:00:00Z