Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
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Cytokine networking of chondrocyte dedifferentiation in vitro and its implications for cell-based cartilage therapyCaesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes.Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis.Dietary Fat Intake and Radiographic Progression of Knee Osteoarthritis: Data From the Osteoarthritis Initiative.Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines and matrix-degrading enzymes in vitro.Muscle cells enhance resistance to pro-inflammatory cytokine-induced cartilage destruction.Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford StudySignaling pathways in cartilage repair.The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degenerationLuteolin Inhibits the Activity, Secretion and Gene Expression of MMP-3 in Cultured Articular Chondrocytes and Production of MMP-3 in the Rat KneeShear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes.Cordycepin prevented IL-β-induced expression of inflammatory mediators in human osteoarthritis chondrocytesStem cell-based microphysiological osteochondral system to model tissue response to interleukin-1β.Cartilage thickness in the hip measured by MRI and stereology before and after periacetabular osteotomyCharacterization of the age-dependent intervertebral disc changes in rabbit by correlation between MRI, histology and gene expression.Dimethylarginine dimethylaminohydrolase 2, a newly identified mitochondrial protein modulating nitric oxide synthesis in normal human chondrocytes.Cyclin-dependent kinase 9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokinesVascular disease is associated with facet joint osteoarthritis.Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammationA genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels.Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes.Evidence that bone mineral density plays a role in degenerative disc disease: the UK Twin Spine studyProtective effects of biochanin A on articular cartilage: in vitro and in vivo studies.Diverse expression of selected cytokines and proteinases in synovial fluid obtained from osteoarthritic and healthy human knee joints.Hydrogels and scaffolds for immunomodulationGuidelines for the Design and Conduct of Clinical Studies in Knee Articular Cartilage Repair: International Cartilage Repair Society Recommendations Based on Current Scientific Evidence and Standards of Clinical Care.Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signalingSerum and synovial fluid nesfatin-1 concentration is associated with radiographic severity of knee osteoarthritis.Existing joint erosions increase the risk of joint space narrowing independently of clinical synovitis in patients with early rheumatoid arthritis.Age-dependent alteration of TGF-β signalling in osteoarthritis.Chondroprotective Effects of Wogonin in Experimental Models of Osteoarthritis in vitro and in vivo.Effects of prunetin on the proteolytic activity, secretion and gene expression of MMP-3 in vitro and production of MMP-3 in vivoApigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes.Mechanical and IL-1β Responsive miR-365 Contributes to Osteoarthritis Development by Targeting Histone Deacetylase 4.Role of Chondrocytes in Cartilage Formation, Progression of Osteoarthritis and Cartilage Regeneration.Anti-inflammatory effect of egg white-chalcanthite and purple bamboo salts mixture on arthritis induced by monosodium iodoacetate in Sprague-Dawley rats.Muscle cell-derived factors inhibit inflammatory stimuli-induced damage in hMSC-derived chondrocytesPKCδ null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth.Betulin suppressed interleukin-1β-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of ratInflammation and epigenetic regulation in osteoarthritis.
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Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
@en
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
@nl
type
label
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
@en
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
@nl
prefLabel
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
@en
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
@nl
P2093
P2860
P356
P1476
Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.
@en
P2093
P2860
P304
P356
10.1136/ARD.2008.098764
P407
P478
67 Suppl 3
P577
2008-12-01T00:00:00Z