Saturable small intestinal drug absorption in humans: modeling and interpretation of cefatrizine data.
about
Translating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption.Mechanistic approaches to predicting oral drug absorption.Predictive models for oral drug absorption: from in silico methods to integrated dynamical models.Modeling kinetics of subcellular disposition of chemicals.Population-based mechanistic prediction of oral drug absorptionSimulations of the nonlinear dose dependence for substrates of influx and efflux transporters in the human intestineDrug absorption modeling as a tool to define the strategy in clinical formulation development.Physiologically based pharmacokinetics (PBPK).An update on computational oral absorption simulation.Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption.Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models.Application of a Bayesian approach to physiological modelling of mavoglurant population pharmacokinetics.Influence of drug release properties of conventional solid dosage forms on the systemic exposure of highly soluble drugs.Influence of molecular properties on oral bioavailability of lipophilic drugs - mapping of bulkiness and different measures of polarity.Pharmacokinetic and pharmacodynamic analysis of efavirenz dose reduction using an in vitro-in vivo extrapolation model.In Silico Absorption Analysis of Valacyclovir in Wildtype and Pept1 Knockout Mice Following Oral Dose Escalation.Unequivocal evidence supporting the segregated flow intestinal model that discriminates intestine versus liver first-pass removal with PBPK modeling.
P2860
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P2860
Saturable small intestinal drug absorption in humans: modeling and interpretation of cefatrizine data.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Saturable small intestinal dru ...... pretation of cefatrizine data.
@ast
Saturable small intestinal dru ...... pretation of cefatrizine data.
@en
type
label
Saturable small intestinal dru ...... pretation of cefatrizine data.
@ast
Saturable small intestinal dru ...... pretation of cefatrizine data.
@en
prefLabel
Saturable small intestinal dru ...... pretation of cefatrizine data.
@ast
Saturable small intestinal dru ...... pretation of cefatrizine data.
@en
P1476
Saturable small intestinal dru ...... pretation of cefatrizine data.
@en
P304
P356
10.1016/S0939-6411(97)00088-X
P407
P577
1998-03-01T00:00:00Z