Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase.
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Insights into the molecular evolution of HslU ATPase through biochemical and mutational analysesThe AAA+ superfamily of functionally diverse proteinsFunctional proteolytic complexes of the human mitochondrial ATP-dependent protease, hClpXPUnscrambling an egg: protein disaggregation by AAA+ proteinsCrystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP proteaseCrystal structure of ClpX molecular chaperone from Helicobacter pyloriStructures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine.Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.Structure and mechanism of the hexameric MecA-ClpC molecular machineStructural Dynamics of the MecA-ClpC Complex: A TYPE II AAA+ PROTEIN UNFOLDING MACHINEAnalysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding.Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis.Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machineAdaptor protein controlled oligomerization activates the AAA+ protein ClpCSpecific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in ArabidopsisDisordered proteinaceous machinesHeat resistance mediated by a new plasmid encoded Clp ATPase, ClpK, as a possible novel mechanism for nosocomial persistence of Klebsiella pneumoniae.Genome-wide analysis of rice ClpB/HSP100, ClpC and ClpD genes.The Protein Chaperone ClpX Targets Native and Non-native Aggregated Substrates for Remodeling, Disassembly, and Degradation with ClpPBinding of the ClpA unfoldase opens the axial gate of ClpP peptidaseLocal and global mobility in the ClpA AAA+ chaperone detected by cryo-electron microscopy: functional connotations.The ClpP N-terminus coordinates substrate access with protease active site reactivity.Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY).Synchrotron protein footprinting supports substrate translocation by ClpA via ATP-induced movements of the D2 loop.ClpXP, an ATP-powered unfolding and protein-degradation machineLoss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors.Structure and activation of a heteromeric protease complex.Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease.The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.Subunit asymmetry and roles of conformational switching in the hexameric AAA+ ring of ClpXThe Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ClpC1Mitochondrial Diseases Part II: Mouse models of OXPHOS deficiencies caused by defects in regulatory factors and other components required for mitochondrial function.Sculpting the proteome with AAA(+) proteases and disassembly machines.Molecular machines for protein degradation.A Quality-Control Mechanism Removes Unfit Cells from a Population of Sporulating Bacteria.clpB, a novel member of the Listeria monocytogenes CtsR regulon, is involved in virulence but not in general stress tolerance.Novel insights into the mechanism of chaperone-assisted protein disaggregation.Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteria.
P2860
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P2860
Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Molecular determinants of comp ...... TPases and the ClpP peptidase.
@ast
Molecular determinants of comp ...... TPases and the ClpP peptidase.
@en
type
label
Molecular determinants of comp ...... TPases and the ClpP peptidase.
@ast
Molecular determinants of comp ...... TPases and the ClpP peptidase.
@en
prefLabel
Molecular determinants of comp ...... TPases and the ClpP peptidase.
@ast
Molecular determinants of comp ...... TPases and the ClpP peptidase.
@en
P2093
P356
P1476
Molecular determinants of comp ...... ATPases and the ClpP peptidase
@en
P2093
Fraczkowska K
Levchenko I
Woodruff RV
P304
P356
10.1038/84967
P50
P577
2001-03-01T00:00:00Z