Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
about
Mild cognitive impairment: pathology and mechanisms.α7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimumMemantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's diseaseActivities of nicotinic acetylcholine receptors modulate neurotransmission and synaptic architectureIn vivo evaluation of alpha7 nicotinic acetylcholine receptor agonists [11C]A-582941 and [11C]A-844606 in mice and conscious monkeysCortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine.Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's diseasePeptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid beta.[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys.High throughput electrophysiology with Xenopus oocytesPhysiological concentrations of choline activate native alpha7-containing nicotinic acetylcholine receptors in the presence of PNU-120596 [1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)-urea].A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptidesThe nicotinic acetylcholine receptor: smoking and Alzheimer's disease revisitedAlpha7 nicotinic acetylcholine receptor: a link between inflammation and neurodegeneration.Endogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.Pharmacological characterization of the allosteric modulator desformylflustrabromine and its interaction with alpha4beta2 neuronal nicotinic acetylcholine receptor orthosteric ligands.Normal genetic variation, cognition, and aging.Brain imaging of nicotinic receptors in Alzheimer's disease.Functional α7β2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid β peptides.Pharmacokinetics and safety profile of ispronicline (TC-1734), a new brain nicotinic receptor partial agonist, in young healthy male volunteers.Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation.SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile.Efficacy study of galantamine in possible Alzheimer's disease with or without cerebrovascular disease and vascular dementia in Thai patients: a slow-titration regimenRescue of amyloid-Beta-induced inhibition of nicotinic acetylcholine receptors by a peptide homologous to the nicotine binding domain of the alpha 7 subtype.A type-II positive allosteric modulator of α7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats.Medicinal chemistry approaches for the treatment and prevention of Alzheimer's disease.Methyllycaconitine alleviates amyloid-β peptides-induced cytotoxicity in SH-SY5Y cellsVentral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.Desformylflustrabromine Modulates α4β2 Neuronal Nicotinic Acetylcholine Receptor High- and Low-Sensitivity Isoforms at Allosteric Clefts Containing the β2 SubunitModulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine.Impaired Cholinergic Excitation of Prefrontal Attention Circuitry in the TgCRND8 Model of Alzheimer's DiseaseAcetylcholinesterase inhibitors for the treatment of dementia in Alzheimer's disease: do we need new inhibitors?Neuronal nicotinic acetylcholine receptors serve as sensitive targets that mediate beta-amyloid neurotoxicity.Nicotinic receptors in neurodegeneration.Effect of Aggregated β-Amyloid (1-42) on Synaptic Plasticity of Hippocampal Dentate Gyrus Granule Cells in Vivo.Nonsynaptic chemical transmission through nicotinic acetylcholine receptors.Complex relationships of nicotinic receptor actions and cognitive functions.Original Research: Influence of okadaic acid on hyperphosphorylation of tau and nicotinic acetylcholine receptors in primary neuronsCellular trafficking of nicotinic acetylcholine receptors.
P2860
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P2860
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
@ast
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
@en
type
label
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
@ast
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
@en
prefLabel
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
@ast
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications.
@en
P1476
Nicotinic receptor abnormalities of Alzheimer's disease: therapeutic implications
@en
P304
P356
10.1016/S0006-3223(00)01125-2
P407
P577
2001-02-01T00:00:00Z