Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities.
about
Kinesin-5: cross-bridging mechanism to targeted clinical therapyPhosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cellsStructural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPMAssociation of kinesin light chain with outer dense fibers in a microtubule-independent fashionThe mechanism of spindle assembly: functions of Ran and its target TPX2"HURP on" we're off to the kinetochore!Contribution of noncentrosomal microtubules to spindle assembly in Drosophila spermatocytesCrosstalk between the actin cytoskeleton and Ran-mediated nuclear transport.The Ran Pathway in Drosophila melanogaster MitosisThirty years of search and capture: The complex simplicity of mitotic spindle assemblyMitotic spindle assembly around RCC1-coated beads in Xenopus egg extractsNuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeastChromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cellsEmergent complexity of the cytoskeleton: from single filaments to tissueRanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubulesRan, a GTP-binding protein involved in nucleocytoplasmic transport and microtubule nucleation, relocates from the manchette to the centrosome region during rat spermiogenesisDynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes.Eukaryotic cells and their cell bodies: Cell Theory revisedCENP-32 is required to maintain centrosomal dominance in bipolar spindle assemblyConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Self-organization of intracellular gradients during mitosis.Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its functionPart of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.Ran is required before metaphase for spindle assembly and chromosome alignment and after metaphase for chromosome segregation and spindle midbody organization.A structural model for monastrol inhibition of dimeric kinesin Eg5.Xenopus TACC3/maskin is not required for microtubule stability but is required for anchoring microtubules at the centrosome.Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states.RanGAP1 is a continuous marker of the Arabidopsis cell division planeFunctional overlap of microtubule assembly factors in chromatin-promoted spindle assembly.Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubulesDynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase.Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assemblyDynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2.Microtubule plus-end dynamics in Xenopus egg extract spindles.Chromosomal attachments set length and microtubule number in the Saccharomyces cerevisiae mitotic spindle.Separating centrosomes interact in the absence of associated chromosomes during mitosis in cultured vertebrate cells.The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.Xenopus importin beta validates human importin beta as a cell cycle negative regulatorPhosphorylation by Cdk1 increases the binding of Eg5 to microtubules in vitro and in Xenopus egg extract spindlesHuman RAS superfamily proteins and related GTPases.
P2860
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P2860
Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Ran stimulates spindle assembl ...... e balance of motor activities.
@ast
Ran stimulates spindle assembl ...... e balance of motor activities.
@en
type
label
Ran stimulates spindle assembl ...... e balance of motor activities.
@ast
Ran stimulates spindle assembl ...... e balance of motor activities.
@en
prefLabel
Ran stimulates spindle assembl ...... e balance of motor activities.
@ast
Ran stimulates spindle assembl ...... e balance of motor activities.
@en
P2093
P356
P1433
P1476
Ran stimulates spindle assembl ...... e balance of motor activities.
@en
P2093
C E Walczak
N R Gliksman
S B Lizarraga
P2888
P304
P356
10.1038/35060000
P577
2001-03-01T00:00:00Z
P6179
1045839708