The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. - Wikidata - awgldk - TriplyDB

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

http://www.wikidata.org/entity/Q33214719

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A novel isoform of MAP4 organises the paraxial microtubule array required for muscle cell differentiation Kinesin-5: cross-bridging mechanism to targeted clinical therapy Potential pulmonary effects of engineered carbon nanotubes: in vitro genotoxic effects The mitotic spindle: linking teratogenic effects of Zika virus with human genetics?Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5 MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A Kinesin-5, a mitotic microtubule-associated motor protein, modulates neuronal migration A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding The bipolar assembly domain of the mitotic motor kinesin-5 TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle Pathway of ATP hydrolysis by monomeric kinesin Eg5 Microtubule cross-linking triggers the directional motility of kinesin-5 Force and premature binding of ADP can regulate the processivity of individual Eg5 dimers Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro Kinesin-5 regulates the growth of the axon by acting as a brake on its microtubule array.Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line Hitting the brakes: targeting microtubule motors in cancer Microtubule networks for plant cell division Regulatory mechanisms that control mitotic kinesins The Msd1-Wdr8-Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies.CYK4 promotes antiparallel microtubule bundling by optimizing MKLP1 neck conformation Deletion of the Tail Domain of the Kinesin-5 Cin8 Affects Its Directionality TPX2 Inhibits Eg5 by Interactions with Both Motor and Microtubule.Kinesin-12 motors cooperate to suppress microtubule catastrophes and drive the formation of parallel microtubule bundles.Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry The Drosophila microtubule-associated protein mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal region Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores.The structure of the ternary Eg5–ADP–ispinesib complex The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5 Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family.Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2 Minus-end-directed Kinesin-14 motors align antiparallel microtubules to control metaphase spindle length Motile properties of the bi-directional kinesin-5 Cin8 are affected by phosphorylation in its motor domain.Directional switching of the kinesin Cin8 through motor coupling.Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules.Microtubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control.Anaphase B

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P2860

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

http://www.wikidata.org/entity/Q33214719

description

2005 nî lūn-bûn

@nan

2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

@ast

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

@en

type

label

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

@ast

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

@en

prefLabel

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

@ast

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

@en

P1433

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P1433

P1476

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.

@en

P2093

Benjamin H Kwok

http://www.w3.org/2001/XMLSchema#string

Erwin J G Peterman

http://www.w3.org/2001/XMLSchema#string

Jeffrey H Kim

http://www.w3.org/2001/XMLSchema#string

Lukas C Kapitein

http://www.w3.org/2001/XMLSchema#string

Tarun M Kapoor

http://www.w3.org/2001/XMLSchema#string

P2860

A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles

A bipolar kinesin

The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

Mitotic spindle organization by a plus-end-directed microtubule motor

Microtubule flux and sliding in mitotic spindles of Drosophila embryos.

Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities.

Combining optical trapping and single-molecule fluorescence spectroscopy: enhanced photobleaching of fluorophores.

Spindle assembly in animal cells.

Microtubule motors in mitosis.

P2888

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114-118

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1038/NATURE03503

http://www.w3.org/2001/XMLSchema#string

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P433

7038

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P478

435

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P50

Christoph F Schmidt

P577

2005-05-01T00:00:00Z

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1041315900

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P698

15875026

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