Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration.
about
Rac and Rho GTPases in cancer cell motility controlThe small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreadingRole of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 proteinSemaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1Involvement of nectin in inactivation of integrin alpha(v)beta(3) after the establishment of cell-cell adhesionRecruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesionSelective suppression of in vivo tumorigenicity by semaphorin SEMA3F in lung cancer cellsSyndecans in tumor cell adhesion and signalingChanges in single-molecule integrin dynamics linked to local cellular behavior.PTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP.Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectinIncreased filamin binding to beta-integrin cytoplasmic domains inhibits cell migrationDynamic modules and heterogeneity of function: a lesson from tyrosine kinase receptors in endothelial cellsCaveolin-1 induces lamellipodia formation via an Akt-dependent pathwayBlood vessel tubulogenesis requires Rasip1 regulation of GTPase signalingADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugationMyosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation.A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migrationDiverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis.Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesionsIntegrins in cell migrationConformational epitopes at cadherin calcium-binding sites and p120-catenin phosphorylation regulate cell adhesionIntegrins in cell migration--the actin connection.Integrin signalling in directed cell migration.Matrix-specific suppression of integrin activation in shear stress signaling.Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinaseE-cadherin engagement stimulates proliferation via Rac1Directional persistence of EGF-induced cell migration is associated with stabilization of lamellipodial protrusions.alpha4beta1 integrin regulates lamellipodia protrusion via a focal complex/focal adhesion-independent mechanism.Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell.alpha4 beta1-Integrin regulates directionally persistent cell migration in response to shear flow stimulation.Integrin-mediated protein kinase A activation at the leading edge of migrating cells.Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1.The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signalingThe distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migrationLeader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K.Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activationRigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha.Structural and mechanical functions of integrins.Loss of beta1-integrin enhances TGF-beta1-induced collagen expression in epithelial cells via increased alphavbeta3-integrin and Rac1 activity.
P2860
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P2860
Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Rac recruits high-affinity int ...... in endothelial cell migration.
@ast
Rac recruits high-affinity int ...... in endothelial cell migration.
@en
type
label
Rac recruits high-affinity int ...... in endothelial cell migration.
@ast
Rac recruits high-affinity int ...... in endothelial cell migration.
@en
prefLabel
Rac recruits high-affinity int ...... in endothelial cell migration.
@ast
Rac recruits high-affinity int ...... in endothelial cell migration.
@en
P2093
P356
P1433
P1476
Rac recruits high-affinity int ...... in endothelial cell migration.
@en
P2093
M A Schwartz
S J Shattil
W B Kiosses
P2888
P304
P356
10.1038/35060120
P577
2001-03-01T00:00:00Z
P5875
P6179
1048358548