Capsids are formed in a mutant virus blocked at the maturation site of the UL26 and UL26.5 open reading frames of herpes simplex virus type 1 but are not formed in a null mutant of UL38 (VP19C).
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Localization of herpes simplex virus type 1 UL37 in the Golgi complex requires UL36 but not capsid structures.Amino acids 143 to 150 of the herpes simplex virus type 1 scaffold protein are required for the formation of portal-containing capsids.Herpes simplex virus DNA cleavage and packaging proteins associate with the procapsid prior to its maturation.Evidence for controlled incorporation of herpes simplex virus type 1 UL26 protease into capsidsVisualizing Herpesvirus Procapsids in Living CellsSilencing herpes simplex virus type 1 capsid protein encoding genes by siRNA: a promising antiviral therapeutic approach.Incorporation of the green fluorescent protein into the herpes simplex virus type 1 capsid.The kinetics of VP5 mRNA expression is not critical for viral replication in cultured cells.A null mutation in the UL36 gene of herpes simplex virus type 1 results in accumulation of unenveloped DNA-filled capsids in the cytoplasm of infected cells.A null mutation in the gene encoding the herpes simplex virus type 1 UL37 polypeptide abrogates virus maturation.Functional analysis of the triplex proteins (VP19C and VP23) of herpes simplex virus type 1The first identified nucleocytoplasmic shuttling herpesviral capsid protein: herpes simplex virus type 1 VP19C.Mutation of single hydrophobic residue I27, L35, F39, L58, L65, L67, or L71 in the N terminus of VP5 abolishes interaction with the scaffold protein and prevents closure of herpes simplex virus type 1 capsid shellsAltering the expression kinetics of VP5 results in altered virulence and pathogenesis of herpes simplex virus type 1 in mice.DNA binding and condensation properties of the herpes simplex virus type 1 triplex protein VP19CA domain in the herpes simplex virus 1 triplex protein VP23 is essential for closure of capsid shells into icosahedral structuresEnzymatic activities of human cytomegalovirus maturational protease assemblin and its precursor (pPR, pUL80a) are comparable: [corrected] maximal activity of pPR requires self-interaction through its scaffolding domain.Structural features of the scaffold interaction domain at the N terminus of the major capsid protein (VP5) of herpes simplex virus type 1.Self-assembly of Epstein-Barr virus capsids.Herpes simplex virus type 1 tegument proteins VP1/2 and UL37 are associated with intranuclear capsidsElucidation of the block to herpes simplex virus egress in the absence of tegument protein UL16 reveals a novel interaction with VP22.Visualization of herpes simplex virus type 1 virions using fluorescent colors.Domain Interaction Studies of Herpes Simplex Virus 1 Tegument Protein UL16 Reveal Its Interaction with Mitochondria.Residues of VP26 of herpes simplex virus type 1 that are required for its interaction with capsids.Small capsid protein pORF65 is essential for assembly of Kaposi's sarcoma-associated herpesvirus capsids.The N terminus of the herpes simplex virus type 1 triplex protein, VP19C, cannot be detected on the surface of the capsid shell by using an antibody (hemagglutinin) epitope tag.Expression of the HSV-1 capsid protein VP19C in Escherichia coli: a single amino acid change overcomes an expression block of the full-length polypeptide.Induced structure of a helical switch as a mechanism to regulate enzymatic activity.
P2860
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P2860
Capsids are formed in a mutant virus blocked at the maturation site of the UL26 and UL26.5 open reading frames of herpes simplex virus type 1 but are not formed in a null mutant of UL38 (VP19C).
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Capsids are formed in a mutant ...... a null mutant of UL38 (VP19C).
@ast
Capsids are formed in a mutant ...... a null mutant of UL38 (VP19C).
@en
type
label
Capsids are formed in a mutant ...... a null mutant of UL38 (VP19C).
@ast
Capsids are formed in a mutant ...... a null mutant of UL38 (VP19C).
@en
prefLabel
Capsids are formed in a mutant ...... a null mutant of UL38 (VP19C).
@ast
Capsids are formed in a mutant ...... a null mutant of UL38 (VP19C).
@en
P356
P1433
P1476
Capsids are formed in a mutant ...... a null mutant of UL38 (VP19C).
@en
P2093
P304
P356
10.1006/VIRO.1997.9005
P407
P577
1998-03-01T00:00:00Z