A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases.
about
Naegeli-Franceschetti-Jadassohn syndrome and dermatopathia pigmentosa reticularis: two allelic ectodermal dysplasias caused by dominant mutations in KRT14Defining the interactions between intermediate filaments and desmosomesPost-translational modifications of intermediate filament proteins: mechanisms and functionsEpidermal transglutaminase (TGase 3) is required for proper hair development, but not the formation of the epidermal barrierA high molecular weight intermediate filament-associated protein in BHK-21 cells is nestin, a type VI intermediate filament protein. Limited co-assembly in vitro to form heteropolymers with type III vimentin and type IV alpha-internexinTrichohyalin mechanically strengthens the hair follicle: multiple cross-bridging roles in the inner root shealthFilaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptensCoiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments.Epithelial barrier function: assembly and structural features of the cornified cell envelope.Keratin gene mutations in disorders of human skin and its appendages.The tail domain is essential but the head domain dispensable for C. elegans intermediate filament IFA-2 function.The stratum corneum: structure and function in health and disease.Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging.SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing.Stratum corneum defensive functions: an integrated view.Micromechanical properties of keratin intermediate filament networksInitiation of assembly of the cell envelope barrier structure of stratified squamous epithelia.Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia.Exploring the Nature of Desmosomal Cadherin Associations in 3D.Dissecting the formation, structure and barrier function of the stratum corneum.Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice.Functional analysis of keratin components in the mouse hair follicle inner root sheath.Residues in the 1A rod domain segment and the linker L2 are required for stabilizing the A11 molecular alignment mode in keratin intermediate filaments.Proteome analysis of human hair shaft: from protein identification to posttranslational modification.Addressing substrate glutamine requirements for tissue transglutaminase using substance P analogues.The cornified cell envelope: an important marker of stratum corneum maturation in healthy and dry skin.Expression of keratinocyte transglutaminase in cornea of vitamin A-deficient rats.New facets of keratin K77: interspecies variations of expression and different intracellular location in embryonic and adult skin of humans and mice.Biochemical evidence that small proline-rich proteins and trichohyalin function in epithelia by modulation of the biomechanical properties of their cornified cell envelopes.Disorders of Keratinization
P2860
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P2860
A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A highly conserved lysine resi ...... slinking by transglutaminases.
@ast
A highly conserved lysine resi ...... slinking by transglutaminases.
@en
type
label
A highly conserved lysine resi ...... slinking by transglutaminases.
@ast
A highly conserved lysine resi ...... slinking by transglutaminases.
@en
prefLabel
A highly conserved lysine resi ...... slinking by transglutaminases.
@ast
A highly conserved lysine resi ...... slinking by transglutaminases.
@en
P2093
P2860
P356
P1476
A highly conserved lysine resi ...... slinking by transglutaminases.
@en
P2093
J G Compton
J J Digiovanna
L N Marekov
P M Steinert
P2860
P304
P356
10.1073/PNAS.95.5.2067
P407
P577
1998-03-01T00:00:00Z