Coiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments.
about
Autosomal recessive transmission of a rare KRT74 variant causes hair and nail ectodermal dysplasia: allelism with dominant woolly hair/hypotrichosisConserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assemblyDefining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermathUnique stabilizing interactions identified in the two-stranded α-helical coiled-coil: Crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptideStructural basis for heteromeric assembly and perinuclear organization of keratin filamentsA composite approach towards a complete model of the myosin rodKeratin mutations in patients with epidermolysis bullosa simplex: correlations between phenotype severity and disturbance of intermediate filament molecular structure.An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper.The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease.Characterization of the linker 2 region in human vimentin using site-directed spin labeling and electron paramagnetic resonance.Characterization of structural changes in vimentin bearing an epidermolysis bullosa simplex-like mutation using site-directed spin labeling and electron paramagnetic resonance.Sequence-resolved free energy profiles of stress-bearing vimentin intermediate filaments.Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stagesAlexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability.Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV).The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27In vitro assembly and structure of trichocyte keratin intermediate filaments: a novel role for stabilization by disulfide bonding.Describing the structure and assembly of protein filaments by EPR spectroscopy of spin-labeled side chains.Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia.Keratinization and its disorders.The Structure and Topology of α-Helical Coiled Coils.Structural Dynamics of the Vimentin Coiled-coil Contact Regions Involved in Filament Assembly as Revealed by Hydrogen-Deuterium Exchange.Exploration of novel motifs derived from mouse cDNA sequences.Homo- and heteropolymer self-assembly of recombinant trichocytic keratins.Induction of p38, tumour necrosis factor-α and RANTES by mechanical stretching of keratinocytes expressing mutant keratin 10R156H.
P2860
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P2860
Coiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments.
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2000 nî lūn-bûn
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name
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@ast
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@en
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@nl
type
label
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@ast
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@en
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@nl
prefLabel
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@ast
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@en
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@nl
P2093
P2860
P356
P1476
Coiled-coil trigger motifs in ...... eratin intermediate filaments.
@en
P2093
L N Marekov
M I Morasso
P M Steinert
P2860
P304
P356
10.1091/MBC.11.10.3539
P577
2000-10-01T00:00:00Z