Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
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RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferationMolecular basis for interaction of let-7 microRNAs with Lin28The biology of DHX9 and its potential as a therapeutic targetThe RNA helicase A in malignant transformationLin-28 regulates oogenesis and muscle formation in Drosophila melanogasterStructural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28What Is the Impact of mRNA 5' TL Heterogeneity on Translational Start Site Selection and the Mammalian Cellular Phenotype?Lin28: primal regulator of growth and metabolism in stem cellsAn RNA-binding Protein, Lin28, Recognizes and Remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs It RegulatesHuman Nup98 regulates the localization and activity of DExH/D-box helicase DHX9A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs.Oncogenic mechanisms of Lin28 in breast cancer: new functions and therapeutic opportunities.Divergent LIN28-mRNA associations result in translational suppression upon the initiation of differentiation.Atomistic mechanism of microRNA translation upregulation via molecular dynamics simulationsThe RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cellsShort loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28.Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancerHow does Lin28 let-7 control development and disease?Aire promotes the self-renewal of embryonic stem cells through Lin28.Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironmentA long non-coding RNA interacts with Gfra1 and maintains survival of mouse spermatogonial stem cellsRoles of helicases in translation initiation: a mechanistic view.Lin28 and let-7: roles and regulation in liver diseases.Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA.Multi-level regulation of cellular recognition of viral dsRNA.Mechanisms of Lin28-mediated miRNA and mRNA regulation--a structural and functional perspective.Competition and collaboration between RNA-binding proteins and microRNAs.In vitro and in vivo analysis of the interaction between RNA helicase A and HIV-1 RNA.Lin28: an emerging important oncogene connecting several aspects of cancer.Lin28 induces resistance to anti-androgens via promotion of AR splice variant generation.Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.Lin28 regulates HER2 and promotes malignancy through multiple mechanisms.Determinants of mRNA recognition and translation regulation by Lin28.Does Lin28 Antagonize miRNA-Mediated Repression by Displacing miRISC from Target mRNAs?Drosha mediates destabilization of Lin28 mRNA targets.Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models.
P2860
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P2860
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
@ast
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
@en
type
label
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
@ast
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
@en
prefLabel
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
@ast
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
@en
P2093
P2860
P921
P356
P1476
Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes.
@en
P2093
Jianyu Jin
Kathleen Boris-Lawrie
Shuping Peng
Xin-Xiang Lei
Yingqun Huang
P2860
P304
P356
10.1093/NAR/GKQ1350
P407
P577
2011-01-18T00:00:00Z