Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.
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Popeye domain-containing proteins and stress-mediated modulation of cardiac pacemakingBeat-to-Beat Variation in Periodicity of Local Calcium Releases Contributes to Intrinsic Variations of Spontaneous Cycle Length in Isolated Single Sinoatrial Node CellsThe importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeatThe mitochondrial Na+-Ca2+ exchanger, NCLX, regulates automaticity of HL-1 cardiomyocytes.Hierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node cells.RyR2R420Q catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism.Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivationFunctional role of voltage gated Ca(2+) channels in heart automaticity.Potential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firingCalsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.Burst pacemaker activity of the sinoatrial node in sodium-calcium exchanger knockout mice.Impaired signaling intrinsic to sinoatrial node pacemaker cells affects heart rate variability during cardiac disease.STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.The fractal-like complexity of heart rate variability beyond neurotransmitters and autonomic receptors: signaling intrinsic to sinoatrial node pacemaker cellsAbnormal Ca(2+) homeostasis, atrial arrhythmogenesis, and sinus node dysfunction in murine hearts modeling RyR2 modificationIon channel-kinase TRPM7 is required for maintaining cardiac automaticity.Pacemaker gene mutations, bradycardia, arrhythmias and the coupled clock theory.SK4 K+ channels are therapeutic targets for the treatment of cardiac arrhythmiasT-type channels in the sino-atrial and atrioventricular pacemaker mechanism.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Ablation of the cardiac ryanodine receptor phospho-site Ser2808 does not alter the adrenergic response or the progression to heart failure in mice. Elimination of the genetic background as critical variable.R4496C RyR2 mutation impairs atrial and ventricular contractility.Contribution of small conductance K+ channels to sinoatrial node pacemaker activity: insights from atrial-specific Na+ /Ca2+ exchange knockout mice.Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell type specific expression of Casq2 in the CPVT2 phenotype.Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.L-type Cav1.3 channels regulate ryanodine receptor-dependent Ca2+ release during sino-atrial node pacemaker activity.A delayed diagnosis of catecholaminergic polymorphic ventricular tachycardia with a mutant of RYR2 at c.7580T>G for 6 years in a 9-year-old child.Chromosome 4q25 Variant rs6817105 Bring Sinus Node Dysfunction and Left Atrial Enlargement
P2860
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P2860
Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.
description
2012 nî lūn-bûn
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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Paradoxical effect of increase ...... rphic ventricular tachycardia.
@ast
Paradoxical effect of increase ...... rphic ventricular tachycardia.
@en
type
label
Paradoxical effect of increase ...... rphic ventricular tachycardia.
@ast
Paradoxical effect of increase ...... rphic ventricular tachycardia.
@en
prefLabel
Paradoxical effect of increase ...... rphic ventricular tachycardia.
@ast
Paradoxical effect of increase ...... rphic ventricular tachycardia.
@en
P2093
P2860
P50
P921
P1433
P1476
Paradoxical effect of increase ...... orphic ventricular tachycardia
@en
P2093
Ana María Gómez
Esther Zorio
Patricia Neco
Silvia G Priori
Sylvain Richard
P2860
P304
P356
10.1161/CIRCULATIONAHA.111.075382
P407
P577
2012-06-18T00:00:00Z