Purification and molecular identification of the human hyaluronan receptor for endocytosis.
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Peritoneal tumor carcinomatosis: pharmacological targeting with hyaluronan-based bioconjugates overcomes therapeutic indications of current drugsN-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronanExpression, processing, and glycosaminoglycan binding activity of the recombinant human 315-kDa hyaluronic acid receptor for endocytosis (HARE).Hyaluronan as an immune regulator in human diseases.Tissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen.Hyaluronic acid receptor Stabilin-2 regulates Erk phosphorylation and arterial--venous differentiation in zebrafish.HARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs.Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves.Stabilin-1, a homeostatic scavenger receptor with multiple functions.The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans.The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermatan sulfate, and CS-E.Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins.Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valvesHyaluronic acid receptor for endocytosis (HARE)-mediated endocytosis of hyaluronan, heparin, dermatan sulfate, and acetylated low density lipoprotein (AcLDL), but not chondroitin sulfate types A, C, D, or E, activates NF-κB-regulated gene expressionCharacterization of the recombinant rat 175-kDa hyaluronan receptor for endocytosis (HARE).The hyaluronan receptor for endocytosis mediates hyaluronan-dependent signal transduction via extracellular signal-regulated kinases.The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparinThe cytoplasmic domain of the hyaluronan receptor for endocytosis (HARE) contains multiple endocytic motifs targeting coated pit-mediated internalizationReceptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.STAB2 (FEEL-2) binds ligands
P2860
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P2860
Purification and molecular identification of the human hyaluronan receptor for endocytosis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Purification and molecular ide ...... onan receptor for endocytosis.
@ast
Purification and molecular ide ...... onan receptor for endocytosis.
@en
type
label
Purification and molecular ide ...... onan receptor for endocytosis.
@ast
Purification and molecular ide ...... onan receptor for endocytosis.
@en
prefLabel
Purification and molecular ide ...... onan receptor for endocytosis.
@ast
Purification and molecular ide ...... onan receptor for endocytosis.
@en
P2093
P356
P1433
P1476
Purification and molecular ide ...... onan receptor for endocytosis.
@en
P2093
Amit Saxena
Carl T McGary
Janet A Weigel
Paul H Weigel
P304
P356
10.1093/GLYCOB/CWG029
P577
2002-12-17T00:00:00Z