Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein.
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Tyrosine modifications in agingSequence conservation of apolipoprotein A-I affords novel insights into HDL structure-functionMyeloperoxidase: a front-line defender against phagocytosed microorganismsImmunolocalization of hypochlorite-induced, catalase-bound free radical formation in mouse hepatocytesAcrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.Specific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase.High-speed data reduction, feature detection, and MS/MS spectrum quality assessment of shotgun proteomics data sets using high-resolution mass spectrometryOxidative risk for atherothrombotic cardiovascular disease.Dysfunctional HDL as a diagnostic and therapeutic targetRedox control of asthma: molecular mechanisms and therapeutic opportunities.Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoproteinNovel technologies for the prevention and treatment of dental caries: a patent survey.High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.Effects of a novel pharmacologic inhibitor of myeloperoxidase in a mouse atherosclerosis model.Activation of RidA chaperone function by N-chlorinationIn vitro oxidative footprinting provides insight into apolipoprotein B-100 structure in low-density lipoprotein.Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathwayImidazole catalyzes chlorination by unreactive primary chloramines.Nitric oxide metabolism in asthma pathophysiology.Site-specific oxidation of apolipoprotein A-I impairs cholesterol export by ABCA1, a key cardioprotective function of HDL.Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesionsPyridoxamine protects proteins from damage by hypohalous acids in vitro and in vivo.Preservation of biological function despite oxidative modification of the apolipoprotein A-I mimetic peptide 4F.Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I.Apolipoprotein A-I tryptophan substitution leads to resistance to myeloperoxidase-mediated loss of functionNADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA.The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis.Autoantibodies to posttranslational modifications in rheumatoid arthritis.Protein oxidation: role in signalling and detection by mass spectrometry.Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids.Understanding and applying tyrosine biochemical diversity.Exploring oxidative modifications of tyrosine: an update on mechanisms of formation, advances in analysis and biological consequences.Dysfunctional HDL and atherosclerotic cardiovascular disease.Neutrophil-generated oxidative stress and protein damage in Staphylococcus aureus.Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl).A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages.Apolipoprotein A-I and cholesterol efflux: the good, the bad, and the modified.Chlorinative stress in age-related diseases: a literature review.Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities.
P2860
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P2860
Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Lysine residues direct the chl ...... izes high density lipoprotein.
@ast
Lysine residues direct the chl ...... izes high density lipoprotein.
@en
type
label
Lysine residues direct the chl ...... izes high density lipoprotein.
@ast
Lysine residues direct the chl ...... izes high density lipoprotein.
@en
prefLabel
Lysine residues direct the chl ...... izes high density lipoprotein.
@ast
Lysine residues direct the chl ...... izes high density lipoprotein.
@en
P2093
P2860
P356
P1476
Lysine residues direct the chl ...... izes high density lipoprotein.
@en
P2093
Constanze Bergt
Jay W Heinecke
Nabiha P Huq
Xiaoyun Fu
P2860
P304
P356
10.1074/JBC.M309046200
P407
P577
2003-12-03T00:00:00Z