Inhibition of gap junction activity through the release of the C1B domain of protein kinase Cgamma (PKCgamma) from 14-3-3: identification of PKCgamma-binding sites.
about
STAC3 stably interacts through its C1 domain with CaV1.1 in skeletal muscle triadsp23/Tmp21 associates with protein kinase Cdelta (PKCdelta) and modulates its apoptotic function.14-3-3epsilon contributes to tumour suppression in laryngeal carcinoma by affecting apoptosis and invasionp23/Tmp21 differentially targets the Rac-GAP beta2-chimaerin and protein kinase C via their C1 domainsStructural basis of protein kinase C isoform functionL-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexinsProtein kinase Cepsilon binds peripherin and induces its aggregation, which is accompanied by apoptosis of neuroblastoma cells.Protein kinase C as a stress sensor.Protein kinase C gamma mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions.Protection from ataxia-linked apoptosis by gap junction inhibitorsC1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosisHypoxia-regulated activity of PKCepsilon in the lens.Loss of protein kinase Cgamma in knockout mice and increased retinal sensitivity to hyperbaric oxygen.Tuning the signalling output of protein kinase C.Akt phosphorylates Connexin43 on Ser373, a "mode-1" binding site for 14-3-3.14-3-3 proteins interact with the beta-thymosin repeat protein Csp24Co-treatment with a C1B5 peptide of protein kinase Cγ and a low dose of gemcitabine strongly attenuated pancreatic cancer growth in mice through T cell activation.
P2860
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P2860
Inhibition of gap junction activity through the release of the C1B domain of protein kinase Cgamma (PKCgamma) from 14-3-3: identification of PKCgamma-binding sites.
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Inhibition of gap junction act ...... ion of PKCgamma-binding sites.
@ast
Inhibition of gap junction act ...... ion of PKCgamma-binding sites.
@en
type
label
Inhibition of gap junction act ...... ion of PKCgamma-binding sites.
@ast
Inhibition of gap junction act ...... ion of PKCgamma-binding sites.
@en
prefLabel
Inhibition of gap junction act ...... ion of PKCgamma-binding sites.
@ast
Inhibition of gap junction act ...... ion of PKCgamma-binding sites.
@en
P2093
P2860
P356
P1476
Inhibition of gap junction act ...... ion of PKCgamma-binding sites.
@en
P2093
Dolores J Takemoto
Larry J Takemoto
Thu Annelise Nguyen
P2860
P304
52714-52725
P356
10.1074/JBC.M403040200
P407
P577
2004-09-30T00:00:00Z