Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers.
about
Adenomatous polyposis coli (APC) is required for normal development of skin and thymusManipulation of DNA Repair Proficiency in Mouse Models of Colorectal CancerColorectal cancer models for novel drug discoveryUnderstanding phenotypic variation in rodent models with germline Apc mutationsAnimal models of colorectal cancerAtonal homolog 1 is a tumor suppressor geneThe H19 locus acts in vivo as a tumor suppressorLiver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomasSLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.Diet, microorganisms and their metabolites, and colon cancer.A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.The tumor suppressor Apc controls planar cell polarities central to gut homeostasis.The knockdown of c-myc expression by RNAi inhibits cell proliferation in human colon cancer HT-29 cells in vitro and in vivo.Mouse models of colorectal cancer.Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancerGenetic and Chemical Models of Colorectal Cancer in Mice.Depletion of p21-activated kinase 1 up-regulates the immune system of APC∆14/+ mice and inhibits intestinal tumorigenesis.Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration.Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families.Animal models of gastrointestinal and liver diseases. New mouse models for studying dietary prevention of colorectal cancerGeneration of a transgenic mouse for colorectal cancer research with intestinal cre expression limited to the large intestineComplex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis.Complete deletion of Apc results in severe polyposis in mice.Novel translational strategies in colorectal cancer research.Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.The functional role of long non-coding RNA in human carcinomas.Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progressionAdenomatous polyposis coli (APC) is essential for maintaining the integrity of the seminiferous epithelium.Non-cell autonomous effects of targeting inducible PGE2 synthesis during inflammation-associated colon carcinogenesisRegulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas.Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth.Suppression of Hepatocellular Carcinoma by Inhibition of Overexpressed Ornithine AminotransferaseAkkermansia muciniphila and Helicobacter typhlonius modulate intestinal tumor development in mice.Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signalingSurgical Correction of Rectal Prolapse in Laboratory Mice (Mus musculus)Restriction of intestinal stem cell expansion and the regenerative response by YAP.Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.Genetic variation and its role in malignancy
P2860
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P2860
Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers.
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Colorectal cancers in a new mo ...... c and environmental modifiers.
@ast
Colorectal cancers in a new mo ...... c and environmental modifiers.
@en
type
label
Colorectal cancers in a new mo ...... c and environmental modifiers.
@ast
Colorectal cancers in a new mo ...... c and environmental modifiers.
@en
prefLabel
Colorectal cancers in a new mo ...... c and environmental modifiers.
@ast
Colorectal cancers in a new mo ...... c and environmental modifiers.
@en
P2093
P2860
P1476
Colorectal cancers in a new mo ...... c and environmental modifiers.
@en
P2093
Béatrice Romagnolo
Christine Perret
Christophe Houbron
Cécile Godard
Dominique Berrebi
Ghislaine Hamard
Marco Giovannini
Michiko Niwa-Kawakita
Sabine Colnot
Servane Le Plenier
P2860
P2888
P304
P356
10.1038/LABINVEST.3700180
P577
2004-12-01T00:00:00Z
P5875
P6179
1016391247