about
What fraction of the human genome is functional?Functionality or transcriptional noise? Evidence for selection within long noncoding RNAsSelective constraint on noncoding regions of hominid genomes.Breaking bad: The mutagenic effect of DNA repairToward a selection theory of molecular evolutionThe mutational spectrum of non-CpG DNA varies with CpG contentNatural Selection and Functional Potentials of Human Noncoding Elements Revealed by Analysis of Next Generation Sequencing DataEffect of the assignment of ancestral CpG state on the estimation of nucleotide substitution rates in mammalsHeterotachy in mammalian promoter evolution.Genomic selective constraints in murid noncoding DNAAdaptive evolution of conserved noncoding elements in mammals.A macaque's-eye view of human insertions and deletions: differences in mechanisms.Analysis of sequence conservation at nucleotide resolutionMutations of different molecular origins exhibit contrasting patterns of regional substitution rate variation.Measuring the prevalence of regional mutation rates: an analysis of silent substitutions in mammals, fungi, and insects.Selective constraints in experimentally defined primate regulatory regions.Hypermutable non-synonymous sites are under stronger negative selectionCryptic variation in the human mutation rate.Weak preservation of local neutral substitution rates across mammalian genomes.Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergenceNew words in human mutagenesis.Late replicating domains are highly recombining in females but have low male recombination rates: implications for isochore evolutionEvolutionary divergence of exon flanks: a dissection of mutability and selection.A genome-wide view of mutation rate co-variation using multivariate analyses.Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content.The effects of chromatin organization on variation in mutation rates in the genome.The genomic landscape of short insertion and deletion polymorphisms in the chicken (Gallus gallus) Genome: a high frequency of deletions in tandem duplicates.Widely distributed noncoding purifying selection in the human genome.Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion.The effect of variation in the effective population size on the rate of adaptive molecular evolution in eukaryotes.Simulating Next-Generation Sequencing Datasets from Empirical Mutation and Sequencing Models.The genome-wide determinants of human and chimpanzee microsatellite evolution.Molecular features and functional constraints in the evolution of the mammalian X chromosome.Sequence context affects the rate of short insertions and deletions in flies and primates.Is there an acceleration of the CpG transition rate during the mammalian radiation?Human-macaque comparisons illuminate variation in neutral substitution rates.Segmenting the human genome based on states of neutral genetic divergenceMultiplex padlock targeted sequencing reveals human hypermutable CpG variations.Identification of deleterious mutations within three human genomes.Variation in the mutation rate across mammalian genomes.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The scale of mutational variation in the murid genome
@ast
The scale of mutational variation in the murid genome
@en
type
label
The scale of mutational variation in the murid genome
@ast
The scale of mutational variation in the murid genome
@en
prefLabel
The scale of mutational variation in the murid genome
@ast
The scale of mutational variation in the murid genome
@en
P2860
P356
P1433
P1476
The scale of mutational variation in the murid genome
@en
P2093
Peter D Keightley
P2860
P304
P356
10.1101/GR.3895005
P577
2005-07-15T00:00:00Z