p53 transcriptional activation domain: a molecular chameleon?
about
Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damageMechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domainsDisorder predictors also predict backbone dynamics for a family of disordered proteinsDNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repairA small molecule directly inhibits the p53 transactivation domain from binding to replication protein A.Structural divergence is more extensive than sequence divergence for a family of intrinsically disordered proteins.Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damageThe contribution of transactivation subdomains 1 and 2 to p53-induced gene expression is heterogeneous but not subdomain-specificHistone modifications affect differential regulation of TGFβ- induced NADPH oxidase 4 (NOX4) by wild-type and mutant p53.Understanding the structural ensembles of a highly extended disordered protein.Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes.Interference with p53 functions in human viral infections, a target for novel antiviral strategies?Reviving the guardian of the genome: Small molecule activators of p53.Cross talk between stimulated NF-kappaB and the tumor suppressor p53.MDM2 chaperones the p53 tumor suppressor.Hypoxia pathway genetic variants predict survival of non-small-cell lung cancer patients receiving platinum-based chemotherapy.Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding.A robust approach for analyzing a heterogeneous structural ensemble.p53 binds the mdmx mRNA and controls its translation.
P2860
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P2860
p53 transcriptional activation domain: a molecular chameleon?
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
p53 transcriptional activation domain: a molecular chameleon?
@ast
p53 transcriptional activation domain: a molecular chameleon?
@en
type
label
p53 transcriptional activation domain: a molecular chameleon?
@ast
p53 transcriptional activation domain: a molecular chameleon?
@en
prefLabel
p53 transcriptional activation domain: a molecular chameleon?
@ast
p53 transcriptional activation domain: a molecular chameleon?
@en
P2093
P356
P1433
P1476
p53 transcriptional activation domain: a molecular chameleon?
@en
P2093
Ayeda Ayed
Elena Bochkareva
Gwan-Su Yi
Lilia Kaustov
P304
P356
10.4161/CC.5.5.2489
P577
2006-03-01T00:00:00Z