Engineering stability into Escherichia coli secreted Fabs leads to increased functional expression.
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How protein recognizes ladder-like polycyclic ethers. Interactions between ciguatoxin (CTX3C) fragments and its specific antibody 10C9Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structureAPEx 2-hybrid, a quantitative protein-protein interaction assay for antibody discovery and engineeringThermostable llama single domain antibodies for detection of botulinum A neurotoxin complexEngineering of stable bispecific antibodies targeting IL-17A and IL-23.Stability engineering of scFvs for the development of bispecific and multivalent antibodies.Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activityIncreased Fab thermoresistance via VH-targeted directed evolution.Optimizing antibody expression by using the naturally occurring framework diversity in a live bacterial antibody display systemMicrocalorimetry: a response to challenges in modern biotechnology.Comparing domain interactions within antibody Fabs with kappa and lambda light chains.Generic approach for the generation of stable humanized single-chain Fv fragments from rabbit monoclonal antibodies.Relative stabilities of IgG1 and IgG4 Fab domains: influence of the light-heavy interchain disulfide bond architectureAdvanced analyses of kinetic stabilities of iggs modified by mutations and glycosylationEngineering an improved IgG4 molecule with reduced disulfide bond heterogeneity and increased Fab domain thermal stability.Increasing stability of antibody via antibody engineering: stability engineering on an anti-hVEGF.Structural and energetic hot-spots for the interaction between a ladder-like polycyclic ether and the anti-ciguatoxin antibody 10C9Fab.Highly covarying residues have a functional role in antibody constant domains.
P2860
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P2860
Engineering stability into Escherichia coli secreted Fabs leads to increased functional expression.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Engineering stability into Esc ...... creased functional expression.
@ast
Engineering stability into Esc ...... creased functional expression.
@en
type
label
Engineering stability into Esc ...... creased functional expression.
@ast
Engineering stability into Esc ...... creased functional expression.
@en
prefLabel
Engineering stability into Esc ...... creased functional expression.
@ast
Engineering stability into Esc ...... creased functional expression.
@en
P2093
P356
P1476
Engineering stability into Esc ...... creased functional expression.
@en
P2093
Bruce E Kimmel
David Gustafson
Geneviève Hansen
Jared Salbato
John Poland
Marikka Elia
P304
P356
10.1093/PROTEIN/GZL016
P577
2006-05-03T00:00:00Z