Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
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C. elegans in high-throughput drug discoveryAngiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life SpanThe anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespanins-7 Gene expression is partially regulated by the DAF-16/IIS signaling pathway in Caenorhabditis elegans under celecoxib interventionShould we enhance animals?Chemical activation of a food deprivation signal extends lifespanLifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegansCinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways.Mulberry leaf polyphenols delay aging and regulate fat metabolism via the germline signaling pathway in Caenorhabditis elegansLate-onset temperature reduction can retard the aging process in aged fish via a combined action of an anti-oxidant system and the insulin/insulin-like growth factor 1 signaling pathway.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.High concentration of vitamin E decreases thermosensation and thermotaxis learning and the underlying mechanisms in the nematode Caenorhabditis elegans.Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q.High-throughput screening in the C. elegans nervous system.Fish oil changes the lifespan of Caenorhabditis elegans via lipid peroxidation.Tocotrienols: the emerging face of natural vitamin ECompounds that confer thermal stress resistance and extended lifespan.Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegansRepurposing FDA-approved drugs for anti-aging therapies.Deceptively simple but simply deceptive--Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects.ROS in aging Caenorhabditis elegans: damage or signaling?Natural compounds with anti-ageing activity.Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways.Anti-ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery.The resveratrol derivatives trans-3,5-dimethoxy-4-fluoro-4'-hydroxystilbene and trans-2,4',5-trihydroxystilbene decrease oxidative stress and prolong lifespan in Caenorhabditis elegans.Current Perspective in the Discovery of Anti-aging Agents from Natural Products.Only one of a wide assortment of manganese-containing SOD mimicking compounds rescues the slow aerobic growth phenotypes of both Escherichia coli and Saccharomyces cerevisiae strains lacking superoxide dismutase enzymes.Modeling type 2 diabetes-like hyperglycemia in C. elegans on a microdevice.The Longevity Properties of 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose from Curcuma longa in Caenorhabditis elegansCatalpol Modulates Lifespan via DAF-16/FOXO and SKN-1/Nrf2 Activation in Caenorhabditis elegans.Whole apple extracts increase lifespan, healthspan and resistance to stress in Caenorhabditis elegans.Identification of a previously undetected metabolic defect in the Complex II Caenorhabditis elegans mev-1 mutant strain using respiratory control analysis.Multiparameter evaluation of the longevity in C. elegans under stress using an integrated microfluidic device.Valproic acid extends Caenorhabditis elegans lifespan.A DAF-16/FoxO3a-dependent longevity signal is initiated by antioxidants.Effect of resveratrol and pterostilbene on aging and longevity.Lifespan extension in Caenorhabiditis elegans by several traditional Chinese medicine formulas.Resveratrol Requires Red Wine Polyphenols for Optimum Antioxidant Activity.Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms.Probing the anti-aging role of polydatin in Caenorhabditis elegans on a chip.
P2860
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P2860
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
@ast
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
@en
type
label
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
@ast
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
@en
prefLabel
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
@ast
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
@en
P2093
P1476
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
@en
P2093
James J Collins
Kerry Kornfeld
Kimberley Evason
P304
P356
10.1016/J.EXGER.2006.06.038
P577
2006-07-26T00:00:00Z