about
Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets.1,3-Diazepanes of natural product-like complexity from cyanamide-induced rearrangement of epoxy-delta-lactams.Targeting RNA by small molecules: comparative structural and thermodynamic aspects of aristololactam-β-D-glucoside and daunomycin binding to tRNA(phe)Amino acid recognition and gene regulation by riboswitches.Histidine affinity chromatography-based methodology for the simultaneous isolation of Escherichia coli small and ribosomal RNA.Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: binding aspects and implications for drug design.Novel insights of structure-based modeling for RNA-targeted drug discovery.Advances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy.Binding of the 9-O-N-aryl/arylalkyl amino carbonyl methyl substituted berberine analogs to tRNA(phe.).The Cech Symposium: a celebration of 25 years of ribozymes, 10 years of TERT, and 60 years of Tom.Screening for inhibitors of the hepatitis C virus internal ribosome entry site RNA.Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication.Strategies for the design of RNA-binding small molecules.Binding-interaction prediction of RNA-binding ligands.RNA targeting by small molecules: Binding of protoberberine, benzophenanthridine and aristolochia alkaloids to various RNA structures.MicroRNAs as mediators of cardiovascular disease: Targets to be manipulatedArtificial nucleobase-amino acid conjugates: a new class of TAR RNA binding agents.Targeting different RNA motifs by beta carboline alkaloid, harmalol: a comparative photophysical, calorimetric, and molecular docking approach.Targeting microRNAs with small molecules: from dream to reality.Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1).Binding of phenazinium dye safranin T to polyriboadenylic acid: spectroscopic and thermodynamic study.Nature of guanine oxidation in RNA via the flash-quench technique versus direct oxidation by a metal oxo complex.Synthesis and stereospecificity of 4,5-disubstituted oxazolidinone ligands binding to T-box riboswitch RNA.Probing the binding of two sugar bearing anticancer agents aristololactam-β-(D)-glucoside and daunomycin to double stranded RNA polynucleotides: a combined spectroscopic and calorimetric study.Design of tRNA(Lys)3 ligands: fragment evolution and linker selection guided by NMR spectroscopy.Binding affinity and in vitro cytotoxicity of harmaline targeting different motifs of nucleic acids: An ultimate drug designing approach.Exploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNAIdentification of Ligands for the Tau Exon 10 Splicing Regulatory Element RNA by Using Dynamic Combinatorial Chemistry
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Towards the discovery of drug-like RNA ligands?
@ast
Towards the discovery of drug-like RNA ligands?
@en
Towards the discovery of drug-like RNA ligands?
@nl
type
label
Towards the discovery of drug-like RNA ligands?
@ast
Towards the discovery of drug-like RNA ligands?
@en
Towards the discovery of drug-like RNA ligands?
@nl
prefLabel
Towards the discovery of drug-like RNA ligands?
@ast
Towards the discovery of drug-like RNA ligands?
@en
Towards the discovery of drug-like RNA ligands?
@nl
P1433
P1476
Towards the discovery of drug-like RNA ligands?
@en
P2093
Fareed Aboul-Ela
Natalia Matassova
P304
P356
10.1016/J.DRUDIS.2006.09.001
P577
2006-09-18T00:00:00Z