Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis.
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FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome.SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomasTargeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathwayRegulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signalingVEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancerLoss of the SSeCKS/Gravin/AKAP12 gene results in prostatic hyperplasiaTransient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53.Molecular genetics of prostate cancer: new prospects for old challengesMolecular pathways and targets in prostate cancerA three-protein biomarker panel assessed in diagnostic tissue predicts death from prostate cancer for men with localized disease.Apoptosis, autophagy, necroptosis, and cancer metastasisPTEN protein loss and clinical outcome from castration-resistant prostate cancer treated with abiraterone acetate.Loss of PLZF expression in prostate cancer by immunohistochemistry correlates with tumor aggressiveness and metastasis.Loss of PTEN is associated with elevated EGFR and HER2 expression and worse prognosis in salivary gland cancerLoss of Wave1 gene defines a subtype of lethal prostate cancerMouse models of advanced spontaneous metastasis for experimental therapeutics.Germ-line sequence variants of PTEN do not have an important role in hereditary and non-hereditary prostate cancer susceptibility.Akt1 mediates prostate cancer cell microinvasion and chemotaxis to metastatic stimuli via integrin β₃ affinity modulation.Protein tyrosine phosphatases: new markers and targets in oncology?Personalized management in low-risk prostate cancer: the role of biomarkers.Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implicationsPrognostic value of PTEN loss in men with conservatively managed localised prostate cancer.PI3 kinase/AKT pathway as a therapeutic target in multiple myeloma.A phase II study evaluating the toxicity and efficacy of single-agent temsirolimus in chemotherapy-naïve castration-resistant prostate cancerFluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression.Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cellsIntegrin signaling aberrations in prostate cancer.Recent developments in prostate cancer biomarker research: therapeutic implications.Disruption of prostate epithelial differentiation pathways and prostate cancer development.The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way.Prognostic and predictive biomarkers in prostate cancer.PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patientsExpression and clinical significance of FAK, ILK, and PTEN in salivary adenoid cystic carcinoma.Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer.Anticancer effect of deoxypodophyllotoxin induces apoptosis of human prostate cancer cells.PTEN Loss as Determined by Clinical-grade Immunohistochemistry Assay Is Associated with Worse Recurrence-free Survival in Prostate Cancer.Castration-resistant prostate cancer: targeted therapies and individualized treatmentMolecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapyProstate Cancer - What's New?
P2860
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P2860
Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
Complete loss of PTEN expressi ...... or prostate cancer metastasis.
@ast
Complete loss of PTEN expressi ...... or prostate cancer metastasis.
@en
type
label
Complete loss of PTEN expressi ...... or prostate cancer metastasis.
@ast
Complete loss of PTEN expressi ...... or prostate cancer metastasis.
@en
prefLabel
Complete loss of PTEN expressi ...... or prostate cancer metastasis.
@ast
Complete loss of PTEN expressi ...... or prostate cancer metastasis.
@en
P2093
P356
P1476
Complete loss of PTEN expressi ...... or prostate cancer metastasis.
@en
P2093
Catherine Capesius
Christiane Margue
Gérard Grignard
Martine Schmitz
Michel Nathan
Nelly Kieffer
René Scheiden
Sandro Giacchi
Walter Dippel
P304
P356
10.1002/IJC.22359
P50
P577
2007-03-01T00:00:00Z