A high-throughput screen for compounds that inhibit aggregation of the Alzheimer's peptide.
about
Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal modelsFluorescent Proteins as Biomarkers and Biosensors: Throwing Color Lights on Molecular and Cellular ProcessesAutoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometryInhibition of IAPP Aggregation and Toxicity by Natural Products and DerivativesGenetic selection designed to stabilize proteins uncovers a chaperone called SpyAmyloid-precursor-protein-lowering small molecules for disease modifying therapy of Alzheimer's diseaseBeta-barrel scaffold of fluorescent proteins: folding, stability and role in chromophore formation.Antiparallel triple-strand architecture for prefibrillar Aβ42 oligomersA revisited folding reporter for quantitative assay of protein misfolding and aggregation in mammalian cells.Techniques for Monitoring Protein Misfolding and Aggregation in Vitro and in Living CellsNew molecular reporters for rapid protein folding assaysDiscovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility.Inhibition of Abeta42 aggregation using peptides selected from combinatorial libraries.Selection for nonamyloidogenic mutants of islet amyloid polypeptide (IAPP) identifies an extended region for amyloidogenicity.Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity.Development and validation of a yeast high-throughput screen for inhibitors of Aβ₄₂ oligomerization.Powerful partners: Arabidopsis and chemical genomicsGradated assembly of multiple proteins into supramolecular nanomaterials.Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42Critique of the use of fluorescence-based reporters in Escherichia coli as a screening tool for the identification of peptide inhibitors of Aβ42 aggregation.Mutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide.Short Peptides as Inhibitors of Amyloid AggregationGeneric hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide.Anti-amyloidogenic properties of some phenolic compoundsInvolvement of molecular chaperones and the transcription factor Nrf2 in neuroprotection mediated by para-substituted-4,5-diaryl-3-thiomethyl-1,2,4-triazinesFlow-cytometric screening of aggregation-inhibitors using a fluorescence-assisted intracellular method.A novel inhibitor of amyloid β (Aβ) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease.Generating extracellular amyloid aggregates using E. coli cells.Novel therapeutic strategies for the treatment of protein-misfolding diseases.Biological role of bacterial inclusion bodies: a model for amyloid aggregation.Interfacial self-assembly of amino acids and peptides: scanning tunneling microscopy investigation.Chaperone discovery.Familial Alzheimer's disease modelling using induced pluripotent stem cell technology.Probing Alzheimer amyloid peptide aggregation using a cell-free fluorescent protein refolding method.A bacterial export system for generating extracellular amyloid aggregates.Recent Advances in Stereoselective Drug Targeting.Methods of probing the interactions between small molecules and disordered proteins.Natural product-based amyloid inhibitors.Histidine-Rich Oligopeptides To Lessen Copper-Mediated Amyloid-β Toxicity.Unraveling protein misfolding diseases using model systems
P2860
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P2860
A high-throughput screen for compounds that inhibit aggregation of the Alzheimer's peptide.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A high-throughput screen for c ...... on of the Alzheimer's peptide.
@ast
A high-throughput screen for c ...... on of the Alzheimer's peptide.
@en
type
label
A high-throughput screen for c ...... on of the Alzheimer's peptide.
@ast
A high-throughput screen for c ...... on of the Alzheimer's peptide.
@en
prefLabel
A high-throughput screen for c ...... on of the Alzheimer's peptide.
@ast
A high-throughput screen for c ...... on of the Alzheimer's peptide.
@en
P2093
P356
P1433
P1476
A high-throughput screen for c ...... on of the Alzheimer's peptide.
@en
P2093
Dong Jin Kim
Michael H Hecht
Woojin Kim
Yunkyoung Kim
P304
P356
10.1021/CB600135W
P577
2006-08-01T00:00:00Z