F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.
about
A conditional knockout resource for the genome-wide study of mouse gene functionMarking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporterDiverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAsMultiple knockout mouse models reveal lincRNAs are required for life and brain developmentHighly efficient generation of biallelic reporter gene knock-in mice via CRISPR-mediated genome editing of ESCsVascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesisConditionals by inversion provide a universal method for the generation of conditional allelesThe endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elementsPostsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.Comparative genetic analysis: the utility of mouse genetic systems for studying human monogenic disease.BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.Effect of stem cell activation, culture media of manipulated embryos, and site of embryo transfer in the production of F0 embryonic stem cell mice.Production of mouse chimeras by injection of embryonic stem cells into the perivitelline space of one-cell stage embryos.Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos.Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.Next-generation mammalian genetics toward organism-level systems biologyTetraploid embryonic stem cells can contribute to the development of chimeric fetuses and chimeric extraembryonic tissuesThe many faces of Pluripotency: in vitro adaptations of a continuum of in vivo states.Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocystGalectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells.Phenotypic annotation of the mouse X chromosomeModelling human regulatory variation in mouse: finding the function in genome-wide association studies and whole-genome sequencingHIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst.The birth of embryonic pluripotency.Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal developmentHuman thrombopoietin knockin mice efficiently support human hematopoiesis in vivoRescue of germline transmission from chimeras by IVF after sperm analysis.Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos.Germline competence of mouse ES and iPS cell lines: Chimera technologies and genetic background.Association of telomere length with authentic pluripotency of ES/iPS cellsPre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infectionEstablishment of epigenetic patterns in developmentOptimization of protocols for derivation of mouse embryonic stem cell lines from refractory strains, including the non obese diabetic mouseComparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts.Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse modelsA role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.Efficient production of chimeric mice from embryonic stem cells injected into 4- to 8-cell and blastocyst embryosErythropoiesis in the absence of adult hemoglobin.
P2860
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P2860
F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@ast
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@en
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@nl
type
label
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@ast
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@en
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@nl
prefLabel
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@ast
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@en
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@nl
P2093
P356
P1433
P1476
F0 generation mice fully deriv ...... immediate phenotypic analyses.
@en
P2093
Anthony T Doré
David M Valenzuela
George D Yancopoulos
Jennifer M Escaravage
Joseph F Hickey
Lakeisha Esau
Melissa G Dominguez
Nicholas W Gale
Niels C Adams
Sean Stevens
P2888
P356
10.1038/NBT1263
P577
2006-12-24T00:00:00Z