Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models
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A comparison of three electrophysiological methods for the assessment of disease status in a mild spinal muscular atrophy mouse modelPharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophyPharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates.Assays for the identification and prioritization of drug candidates for spinal muscular atrophySMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.Spinal muscular atrophy: journeying from bench to bedsideSMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical TrialsSMN deficiency disrupts gastrointestinal and enteric nervous system function in miceSmall Molecules in Development for the Treatment of Spinal Muscular Atrophy.Activin Receptor Type IIB Inhibition Improves Muscle Phenotype and Function in a Mouse Model of Spinal Muscular AtrophySystemic, postsymptomatic antisense oligonucleotide rescues motor unit maturation delay in a new mouse model for type II/III spinal muscular atrophy.Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophyA novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein.Spinal muscular atrophy: an update on therapeutic progressMore than a bystander: the contributions of intrinsic skeletal muscle defects in motor neuron diseases.Cardiac pathology in spinal muscular atrophy: a systematic review.TIA1 is a gender-specific disease modifier of a mild mouse model of spinal muscular atrophy.A Stem Cell Model of the Motor Circuit Uncouples Motor Neuron Death from Hyperexcitability Induced by SMN Deficiency.Gender-Specific Amelioration of SMA Phenotype upon Disruption of a Deep Intronic Structure by an Oligonucleotide.Optimizing mouse models of neurodegenerative disorders: are therapeutics in sight?
P2860
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P2860
Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models
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2012 nî lūn-bûn
@nan
2012年の論文
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
Characterization of behavioral ...... lic series of SMA mouse models
@ast
Characterization of behavioral ...... lic series of SMA mouse models
@en
type
label
Characterization of behavioral ...... lic series of SMA mouse models
@ast
Characterization of behavioral ...... lic series of SMA mouse models
@en
prefLabel
Characterization of behavioral ...... lic series of SMA mouse models
@ast
Characterization of behavioral ...... lic series of SMA mouse models
@en
P2093
P2860
P356
P1476
Characterization of behavioral ...... lic series of SMA mouse models
@en
P2093
Afshin Ghavami
Bassem El-Khodor
Cathleen Lutz
Chien-Ping Ko
Corissa McEwen
Crystal Davis
Daniel Gomez
David D McKemy
Dione Kobayashi
Jose Beltran
P2860
P304
P356
10.1093/HMG/DDS285
P577
2012-07-16T00:00:00Z