about
The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathwaySos-mediated activation of rac1 by p66shcCDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASPMolecular basis for the dual function of Eps8 on actin dynamics: bundling and cappingEps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF)Propagating cell-membrane waves driven by curved activators of actin polymerizationRequirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesisAbi1 is essential for the formation and activation of a WAVE2 signalling complexRegulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complexThe insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticityPalladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cellsIncreased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamicsSCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progressionThe signaling adaptor Eps8 is an essential actin capping protein for dendritic cell migrationEps8 controls actin-based motility by capping the barbed ends of actin filamentsEps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells
P50
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P50
description
onderzoeker
@nl
name
Andrea Disanza
@ast
Andrea Disanza
@en
Andrea Disanza
@es
Andrea Disanza
@nl
Andrea Disanza
@sl
type
label
Andrea Disanza
@ast
Andrea Disanza
@en
Andrea Disanza
@es
Andrea Disanza
@nl
Andrea Disanza
@sl
prefLabel
Andrea Disanza
@ast
Andrea Disanza
@en
Andrea Disanza
@es
Andrea Disanza
@nl
Andrea Disanza
@sl