Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response
about
Immune signaling by RIG-I-like receptorsRecognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon inductionThe measles virus V protein binds to p65 (RelA) to suppress NF-kappaB activityFunction and regulation of retinoic acid-inducible gene-I5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-ITLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetesThe response of mammalian cells to double-stranded RNACell-cell fusion induced by measles virus amplifies the type I interferon response.Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate ImmunityBoth RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human CellsThe regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNARIG-I in RNA virus recognitionInduction of type I interferon by RNA viruses: cellular receptors and their substratesRIG-I and dsRNA-induced IFNbeta activation.Mechanisms of protein kinase PKR-mediated amplification of beta interferon induction by C protein-deficient measles virusConserved charged amino acids within Sendai virus C protein play multiple roles in the evasion of innate immune responsesMolecular biology of rift valley Fever virusRIG-I is required for the inhibition of measles virus by retinoidsMeasles virus-induced suppression of immune responses.RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I.Measles virus suppresses RIG-I-like receptor activation in dendritic cells via DC-SIGN-mediated inhibition of PP1 phosphatasesRNase L releases a small RNA from HCV RNA that refolds into a potent PAMP.Interplay between innate immunity and negative-strand RNA viruses: towards a rational modelRNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in DrosophilaEncephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome.Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine.Short double-stranded RNAs with an overhanging 5' ppp-nucleotide, as found in arenavirus genomes, act as RIG-I decoysEntire genome sequence analysis of genotype IX Newcastle disease viruses reveals their early-genotype phylogenetic position and recent-genotype genome size.Characterization of rotavirus RNAs that activate innate immune signaling through the RIG-I-like receptors.Positive evolutionary selection on the RIG-I-like receptor genes in mammalsThe V protein of canine distemper virus is required for virus replication in human epithelial cells.The inability of wild-type rabies virus to activate dendritic cells is dependent on the glycoprotein and correlates with its low level of the de novo-synthesized leader RNA.In vivo ligands of MDA5 and RIG-I in measles virus-infected cells.Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activationFunctions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity.dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity.RIG-I self-oligomerization is either dispensable or very transient for signal transduction.Measles virus V protein inhibits NLRP3 inflammasome-mediated interleukin-1β secretion.Activation of RIG-I-like receptor signal transduction.
P2860
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P2860
Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Cytosolic 5'-triphosphate ende ...... I-mediated interferon response
@ast
Cytosolic 5'-triphosphate ende ...... I-mediated interferon response
@en
type
label
Cytosolic 5'-triphosphate ende ...... I-mediated interferon response
@ast
Cytosolic 5'-triphosphate ende ...... I-mediated interferon response
@en
prefLabel
Cytosolic 5'-triphosphate ende ...... I-mediated interferon response
@ast
Cytosolic 5'-triphosphate ende ...... I-mediated interferon response
@en
P2093
P2860
P1433
P1476
Cytosolic 5'-triphosphate ende ...... I-mediated interferon response
@en
P2093
Florence Herschke
Hélène Valentin
Sonia Longhi
Sébastien Plumet
P2860
P356
10.1371/JOURNAL.PONE.0000279
P407
P577
2007-03-14T00:00:00Z