Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
about
High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical librariesDroplet microfluidic technology for single-cell high-throughput screeningSelection of bead-displayed, PNA-encoded chemicals.Translation of DNA into a library of 13,000 synthetic small-molecule macrocycles suitable for in vitro selection.Reactivity-dependent PCR: direct, solution-phase in vitro selection for bond formation.Review article: high-throughput affinity-based technologies for small-molecule drug discovery.In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitorsPhotoaffinity labeling of transcription factors by DNA-templated crosslinking.A sequential strand-displacement strategy enables efficient six-step DNA-templated synthesis.20 years of DNA-encoded chemical libraries.The great screen anomaly--a new frontier in product discovery through functional metagenomics.Novel selection methods for DNA-encoded chemical librariesDNA as a versatile chemical component for catalysis, encoding, and stereocontrolAutomated screening for small organic ligands using DNA-encoded chemical libraries.DNA-encoded chemical libraries: foundations and applications in lead discovery.Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View.Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries.Oligonucleotide-Based Systems for Input-Controlled and Non-Covalently Regulated Protein-BindingDNA-guided display of proteins and protein ligands for the interrogation of biology.Multivalency as a chemical organization and action principle.Carbohydrate-PNA and aptamer-PNA conjugates for the spatial screening of lectins and lectin assemblies.Design, preparation, and selection of DNA-encoded dynamic librariesBile Acid Conjugated DNA Chimera that Conditionally Inhibits Carbonic Anhydrase-II in the Presence of MicroRNA-21.DNA-Encoded Chemical Libraries: A Selection System Based On Endowing Organic Compounds with Amplifiable Information.Impact of a Central Scaffold on the Binding Affinity of Fragment Pairs Isolated from DNA-Encoded Self-Assembling Chemical Libraries.A Specific and Covalent JNK-1 Ligand Selected from an Encoded Self-Assembling Chemical Library.DNA as a Tool for Molecular Discovery
P2860
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P2860
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@ast
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@en
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@nl
type
label
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@ast
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@en
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@nl
prefLabel
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@ast
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@en
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@nl
P2093
P356
P1476
Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library.
@en
P2093
Christoph E Dumelin
Samu Melkko
Yixin Zhang
P304
P356
10.1002/ANIE.200700654
P407
P577
2007-01-01T00:00:00Z