Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes.

Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes.

Item
http://www.wikidata.org/entity/Q33307883
Specific small molecule inhibitors of Skp2-mediated p27 degradationAPC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayAmyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells.The ubiquitin system, disease, and drug discovery.Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cellsGenome-wide approaches to systematically identify substrates of the ubiquitin-proteasome pathwayAmyloid Precursor Protein Binding Protein-1 Is Up-regulated in Brains of Tg2576 Mice.Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.SCF ubiquitin ligases in the maintenance of genome stability.TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancerMultimodal mechanism of action for the Cdc34 acidic loop: a case study for why ubiquitin-conjugating enzymes have loops and tailsSmall-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome systemAn update on the current pharmacotherapy for endometrial cancer.
P2860

Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes.

Item
http://www.wikidata.org/entity/Q33307883
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@ast
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@en
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@nl
type
label
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@ast
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@en
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@nl
prefLabel
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@ast
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@en
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P478
P577
P6179
P698
P921
P932
P356
P1433
P1476
Wrenches in the works: drug di ...... in ligase and APC/C complexes.
@en
P2093
P2860
P2888
P304
P31
P356
P478
P577
P6179
P698
P921
P932