Evaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets.

Evaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets.

Item
http://www.wikidata.org/entity/Q33309374
Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate.G(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets.Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2)Protein kinase C[delta] differentially regulates platelet functional responses.Spleen tyrosine kinase: an Src family of non-receptor kinase has multiple functions and represents a valuable therapeutic target in the treatment of autoimmune and inflammatory diseases.Syk inhibitors in clinical development for hematological malignancies.Antagonism of P2Y₁₂ reduces physiological thromboxane levels.
P2860

Evaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets.

Item
http://www.wikidata.org/entity/Q33309374
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@ast
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@en
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@nl
type
label
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@ast
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@en
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@nl
prefLabel
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@ast
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@en
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
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P1433
P1476
Evaluation of [3-(1-methyl-1H- ...... ective inhibitor in platelets.
@en
P2093
P2860
P304
P31
P356
10.1016/J.EJPHAR.2007.11.009
P407
P433
P478
P577
P5875
P698
P932