Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2 activation
about
Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cellsGlimepiride reduces the expression of PrPc, prevents PrPSc formation and protects against prion mediated neurotoxicity in cell lines.Glycosylphosphatidylinositol anchor analogues sequester cholesterol and reduce prion formation.Inhibition of cytosolic Phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III TubulinMonoacylated cellular prion protein modifies cell membranes, inhibits cell signaling, and reduces prion formation.Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains.Prion infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cellsPathogenic prions deviate PrP(C) signaling in neuronal cells and impair A-beta clearanceTarget- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbersNeuroprotective actions of brain aromatase.The role of secretory phospholipase A₂ in the central nervous system and neurological diseases.The cellular prion protein with a monoacylated glycosylphosphatidylinositol anchor modifies cell membranes, inhibits cell signaling and reduces prion formation.Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells.Phospholipase A2 inhibitors protect against prion and Abeta mediated synapse degeneration.Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice.Does the tail wag the dog? How the structure of a glycosylphosphatidylinositol anchor affects prion formation.Glycosylphosphatidylinositols: More than just an anchor?α-Synuclein-induced synapse damage in cultured neurons is mediated by cholesterol-sensitive activation of cytoplasmic phospholipase A2.Modeling the effects of cyclodextrin on intracellular membrane vesicles from Cos-7 cells prepared by sonication and carbonate treatment.
P2860
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P2860
Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2 activation
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Sequestration of free choleste ...... ic phospholipase A2 activation
@ast
Sequestration of free choleste ...... ic phospholipase A2 activation
@en
Sequestration of free choleste ...... c phospholipase A2 activation.
@nl
type
label
Sequestration of free choleste ...... ic phospholipase A2 activation
@ast
Sequestration of free choleste ...... ic phospholipase A2 activation
@en
Sequestration of free choleste ...... c phospholipase A2 activation.
@nl
prefLabel
Sequestration of free choleste ...... ic phospholipase A2 activation
@ast
Sequestration of free choleste ...... ic phospholipase A2 activation
@en
Sequestration of free choleste ...... c phospholipase A2 activation.
@nl
P2860
P356
P1433
P1476
Sequestration of free choleste ...... ic phospholipase A2 activation
@en
P2093
Alun Williams
Clive Bate
P2860
P2888
P356
10.1186/1741-7007-6-8
P577
2008-02-12T00:00:00Z
P5875
P6179
1040897795