Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors.
about
UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activityHdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cellsPTEN inhibits BMI1 function independently of its phosphatase activityHuman melanoma-initiating cells express neural crest nerve growth factor receptor CD271It takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brainNotchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cellsClonal evolution in cancerAssociation of reactive oxygen species levels and radioresistance in cancer stem cellsDownregulation of miRNA-200c links breast cancer stem cells with normal stem cellsTransient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter micec-Jun NH2-terminal kinase is required for lineage-specific differentiation but not stem cell self-renewal.Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.Intrathymic transplantation of bone marrow-derived progenitors provides long-term thymopoiesis.p53 regulates hematopoietic stem cell quiescence.Some hematopoietic stem cells are more equal than others.p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal.Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.Sequential changes at differentiation gene promoters as they become active in a stem cell lineageEx vivo expansion of human hematopoietic stem and progenitor cells.The Regulation of Aging and Longevity: A New and Complex Role of p53.p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.Effects of TP53 mutational status on gene expression patterns across 10 human cancer types.Regulation of murine hematopoietic stem cell quiescence by Dmtf1Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers.Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells.Oncogenesis and cancer stem cells: current opinions and future directions.Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemiaIntegrating physiological regulation with stem cell and tissue homeostasisA small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice.The evolving concept of cancer and metastasis stem cellsLoss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model.CD150(-) Side Population Defines Leukemia Stem Cells in a BALB/c Mouse Model of CML and Is Depleted by Genetic Loss of SIRT1A matter of life and death: self-renewal in stem cells.The p53 pathway in hematopoiesis: lessons from mouse models, implications for humans.Therapeutic targeting of the p53 pathway in cancer stem cells.Faith, heresy and the cancer stem cell hypothesisOxidants, metabolism, and stem cell biologyPUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf.Usp16 contributes to somatic stem-cell defects in Down's syndrome.
P2860
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P2860
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@ast
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@en
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@nl
type
label
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@ast
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@en
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@nl
prefLabel
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@ast
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@en
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@nl
P2093
P356
P1433
P1476
Long-term haematopoietic recon ...... rf-/- multipotent progenitors.
@en
P2093
Dalong Qian
In-Kyung Park
Michael F Clarke
Michael Pihalja
Omobolaji O Akala
P2888
P304
P356
10.1038/NATURE06869
P407
P577
2008-04-16T00:00:00Z
P5875
P6179
1003819214