Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
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Role of Nrf2 in oxidative stress and toxicityMitochondrial Redox Dysfunction and Environmental ExposuresAnimal models of COPD: What do they tell us?Stress-activated cap'n'collar transcription factors in aging and human diseaseNrf2 expression is increased in peripheral blood mononuclear cells derived from mild-moderate ex-smoker COPD patients with persistent oxidative stressNrf2 plays a pivotal role in protection against burn trauma-induced intestinal injury and deathCigarette smoking blocks the protective expression of Nrf2/ARE pathway in peripheral mononuclear cells of young heavy smokers favouring inflammationRNAi Screen for NRF2 Inducers Identifies Targets That Rescue Primary Lung Epithelial Cells from Cigarette Smoke Induced Radical StressOxidative Stress in COPD: Sources, Markers, and Potential MechanismsRole of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicityHistone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity.Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.Induction of heme oxygenase-1, biliverdin reductase and H-ferritin in lung macrophage in smokers with primary spontaneous pneumothorax: role of HIF-1alphaNrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs.Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.Human alveolar epithelial cell injury induced by cigarette smokeExtracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM.Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis.NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction.Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate.Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stressThiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2.Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysemaActivation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers.Oxidants in Acute and Chronic Lung DiseasePolymorphisms of Nrf2, an antioxidative gene, are associated with blood pressure in Japanese.Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patientsRETRACTED: NAD(P)H:quinone oxidoreductase 1 protects lungs from oxidant-induced emphysema in mice.Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective functionOxidative stress induced lung cancer and COPD: opportunities for epigenetic therapy.Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking.Experimental therapeutics of Nrf2 as a target for prevention of bacterial exacerbations in COPDStrategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease.Genetic polymorphism of heme oxygenase 1 promoter in the occurrence and severity of chronic obstructive pulmonary disease: a meta-analysisCigarette smoke-induced induction of antioxidant enzyme activities in airway leukocytes is absent in active smokers with COPD.Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke
P2860
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P2860
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
@ast
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
@en
type
label
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
@ast
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
@en
prefLabel
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
@ast
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
@en
P2093
P356
P1433
P1476
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.
@en
P2093
B Crestani
J Marchal-Sommé
M Fournier
V Leçon-Malas
P304
P356
10.1136/THX.2007.091181
P407
P577
2008-06-17T00:00:00Z