Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin. - Wikidata - awgldk - TriplyDB

Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

http://www.wikidata.org/entity/Q33354615

about

Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1.Loss of Folliculin Disrupts Hematopoietic Stem Cell Quiescence and Homeostasis Resulting in Bone Marrow Failure.Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases AMPK--sensing energy while talking to other signaling pathways.Folliculin directs the formation of a Rab34-RILP complex to control the nutrient-dependent dynamic distribution of lysosomes.Reduced cilia frequencies in human renal cell carcinomas versus neighboring parenchymal tissue.Glycogen: A must have storage to survive stressful emergencies Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.

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P2860

Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

http://www.wikidata.org/entity/Q33354615

description

2013 nî lūn-bûn

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2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

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Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

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Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

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Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

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Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

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Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.

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P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein

Identification and characterization of a novel folliculin-interacting protein FNIP2

Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization

Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling

AMPK phosphorylation of raptor mediates a metabolic checkpoint

A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

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