Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance.
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PEGylated Adenoviruses: From Mice to MonkeysPEGylated helper-dependent adenoviral vectors: highly efficient vectors with an enhanced safety profile.Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors.Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy.Analysis of adenoviral attachment to human platelets.Platelet-adenovirus vs. inert particles interaction: effect on aggregation and the role of platelet membrane receptors.Adenoviral vector immunity: its implications and circumvention strategies.TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses.beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.Current strategies and future directions for eluding adenoviral vector immunitySpecies differences in the pharmacology and toxicology of PEGylated helper-dependent adenovirusUse of DAF-displaying adenovirus vectors reduces induction of transgene- and vector-specific adaptive immune responses in mice.Sustained phenotypic correction in a mouse model of hypoalphalipoproteinemia with a helper-dependent adenovirus vector.Intratumoral delivery of CD154 homolog (Ad-ISF35) induces tumor regression: analysis of vector biodistribution, persistence and gene expressionImproving adenovirus based gene transfer: strategies to accomplish immune evasion.Tropism-modification strategies for targeted gene delivery using adenoviral vectors.Adenoviral p53 gene transfer and gemcitabine in three patients with liver metastases due to advanced pancreatic carcinoma.Stimulation of innate immunity by in vivo cyclic di-GMP synthesis using adenovirus.Adenovirus-platelet interaction in blood causes virus sequestration to the reticuloendothelial system of the liver.Factors influencing retention of adenovirus within tumours following direct intratumoural injection.Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent.
P2860
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P2860
Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Intravenous administration of ...... ng in vivo platelet clearance.
@ast
Intravenous administration of ...... ng in vivo platelet clearance.
@en
type
label
Intravenous administration of ...... ng in vivo platelet clearance.
@ast
Intravenous administration of ...... ng in vivo platelet clearance.
@en
prefLabel
Intravenous administration of ...... ng in vivo platelet clearance.
@ast
Intravenous administration of ...... ng in vivo platelet clearance.
@en
P2093
P2860
P1476
Intravenous administration of ...... ng in vivo platelet clearance.
@en
P2093
Aguilar-Córdova E
Eggerman TL
P2860
P304
P356
10.1046/J.1365-2141.2003.04719.X
P407
P577
2003-12-01T00:00:00Z