Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent.
about
Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune responseA new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic targetVaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responsesComplex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors.Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy.Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factorAdenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo.Adenoviral vector immunity: its implications and circumvention strategies.CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodiesTRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses.beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2.Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor.Development of a targeted gene vector platform based on simian adenovirus serotype 24.Evaluation of innate immunity and vector toxicity following inoculation of bovine, porcine or human adenoviral vectors in a mouse modelClearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complementAn Ad5[E1-, E2b-]-HER2/neu vector induces immune responses and inhibits HER2/neu expressing tumor progression in Ad5 immune mice.Use of DAF-displaying adenovirus vectors reduces induction of transgene- and vector-specific adaptive immune responses in mice.Vaccination with adenovirus serotypes 35, 26, and 48 elicits higher levels of innate cytokine responses than adenovirus serotype 5 in rhesus monkeysAdenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo.Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors.Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43.Improving adenovirus based gene transfer: strategies to accomplish immune evasion.Immune recognition of gene transfer vectors: focus on adenovirus as a paradigm.The importance of coagulation factors binding to adenovirus: historical perspectives and implications for gene delivery.A preliminary and comparative evaluation of a novel Ad5 [E1-, E2b-] recombinant-based vaccine used to induce cell mediated immune responsesStimulation of innate immunity by in vivo cyclic di-GMP synthesis using adenovirus.
P2860
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P2860
Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Wild-type adenoviruses from gr ...... artially complement dependent.
@en
Wild-type adenoviruses from gr ...... artially complement dependent.
@nl
type
label
Wild-type adenoviruses from gr ...... artially complement dependent.
@en
Wild-type adenoviruses from gr ...... artially complement dependent.
@nl
prefLabel
Wild-type adenoviruses from gr ...... artially complement dependent.
@en
Wild-type adenoviruses from gr ...... artially complement dependent.
@nl
P2093
P2860
P356
P1433
P1476
Wild-type adenoviruses from gr ...... artially complement dependent.
@en
P2093
A Amalfitano
D M Appledorn
R Stringer
P2860
P2888
P304
P356
10.1038/GT.2008.18
P577
2008-02-21T00:00:00Z
P5875
P6179
1016028648