The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
about
Ubiquitylation-dependent downregulation of Nck regulates its functional activityAnticoagulation in combination with antiangiogenesis and chemotherapy for cancer patients: evidence and hypothesisTargeting NK Cells for Anticancer Immunotherapy: Clinical and Preclinical ApproachesPhosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancerAXL kinase as a novel target for cancer therapyImmune cell promotion of metastasisNEDD4: a promising target for cancer therapyThe Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer TherapyThe Receptor Tyrosine Kinase AXL in Cancer ProgressionMolecular Pathways: AXL, a Membrane Receptor Mediator of Resistance to TherapyLigand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic ResponseTumor cell dormancyMetastatic colonization by circulating tumour cellsTargeting the TAM Receptors in LeukemiaThe new deal: a potential role for secreted vesicles in innate immunity and tumor progressionOrchestration of angiogenesis by immune cellsA rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis.TAM Receptors Are Not Required for Zika Virus Infection in MiceMicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritisE3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activationOpportunities and limitations of natural killer cells as adoptive therapy for malignant diseaseAn engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.The lung metastatic niche.Targeting metastasis-initiating cells through the fatty acid receptor CD36.Axl as a mediator of cellular growth and survivalA think tank of TINK/TANKs: tumor-infiltrating/tumor-associated natural killer cells in tumor progression and angiogenesis.Molecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment.Cbl-b: Roles in T Cell Tolerance, Proallergic T Cell Development, and Cancer Immunity.TAM receptor signaling in immune homeostasis.The AXL Receptor is a Sensor of Ligand Spatial HeterogeneityWarfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and MetastasisCombined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells.Cbl-b Deficiency in Mice Results in Exacerbation of Acute and Chronic Stages of Allergic Asthma.The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrityInhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS-777607 reduces glioblastoma growth, migration, and invasion in vitro and in vivoThe Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.A prognostic risk model for patients with triple negative breast cancer based on stromal natural killer cells, tumor-associated macrophages and growth-arrest specific protein 6.E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor-mediated antifungal innate immunity
P2860
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P2860
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The E3 ligase Cbl-b and TAM re ...... asis via natural killer cells.
@ast
The E3 ligase Cbl-b and TAM re ...... asis via natural killer cells.
@en
type
label
The E3 ligase Cbl-b and TAM re ...... asis via natural killer cells.
@ast
The E3 ligase Cbl-b and TAM re ...... asis via natural killer cells.
@en
prefLabel
The E3 ligase Cbl-b and TAM re ...... asis via natural killer cells.
@ast
The E3 ligase Cbl-b and TAM re ...... asis via natural killer cells.
@en
P2093
P50
P356
P1433
P1476
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
@en
P2093
Anke Unger
Axel Choidas
Axel Ullrich
Bert M Klebl
Blanka Pranjic
Carsten Schultz-Fademrecht
Dominik Wolf
Gottfried Baier
Jan Eickhoff
Josef M Penninger
P2888
P304
P356
10.1038/NATURE12998
P407
P577
2014-02-19T00:00:00Z