CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
about
Analysis of the genome to personalize therapy for melanomaUpdates of mTOR inhibitorsNext-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategyTargeting the mTOR signaling network for cancer therapyMelanoma: from mutations to medicinePI3K/PTEN signaling in angiogenesis and tumorigenesisClinical activity and safety of combination therapy with temsirolimus and bevacizumab for advanced melanoma: a phase II trial (CTEP 7190/Mel47)MicroRNAs induced in melanoma treated with combination targeted therapy of Temsirolimus and BevacizumabPhase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma.A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer.Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179).Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma.State of melanoma: an historic overview of a field in transition.The PIK3CA gene as a mutated target for cancer therapy.In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways.Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications.Combined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma.Exploiting novel molecular targets in gastrointestinal cancers.Resistance to chemotherapy and molecularly targeted therapies: rationale for combination therapy in malignant melanomaTargeted therapy for melanoma: a primer.Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma.Vertical targeting of the phosphatidylinositol-3 kinase pathway as a strategy for treating melanoma.The Akt-specific inhibitor MK2206 selectively inhibits thyroid cancer cells harboring mutations that can activate the PI3K/Akt pathway.Novel targeted therapies for the treatment of metastatic melanoma.New horizons in melanoma treatment: targeting molecular pathways.A phase II study of gefitinib in patients with metastatic melanoma.Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.Targeted agents for the treatment of metastatic melanoma.The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.Targeting drivers of melanoma with synthetic small molecules and phytochemicals.AKT1 Activation Promotes Development of Melanoma Metastases.Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy.Therapeutic interventions to disrupt the protein synthetic machinery in melanomaMetabolic complications with the use of mTOR inhibitors for cancer therapyInvestigating mammalian target of rapamycin inhibitors for their anticancer properties.Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.New approaches in metastatic melanoma: biological and molecular targeted therapies.
P2860
Q24601008-6B2ECAE5-D740-4C5C-9CEA-A3827323787DQ24607170-DE01320A-A69C-4969-A96F-44FF758BB223Q24628724-0E2A5947-E1CD-455F-9384-0F6311C7A1A7Q24658334-4C513133-AAE8-4F74-88D7-1F541AA916B8Q27024061-2F378118-8E93-4120-BCA5-A4AEBDC1D791Q28383083-4B883B6D-5AFB-4774-A47D-B855C280FE7EQ30412106-AFCFE0CA-1ACE-46BE-B1DA-3081A04F9B22Q30415894-E07A9AE6-9CF7-438A-AC12-84C66FAC64F1Q33383550-F40F7052-5A21-4304-B60B-8F6FDBF994CAQ33389796-3662A079-B95E-4884-8F88-0E72B20AC1FDQ33394687-C3859F61-8AC8-480E-85E8-BCB66B35F64EQ33399049-25CD16E4-2980-4C43-99A8-486D1CFEF03CQ33693906-6C7E4F41-7CAE-48F1-B90B-AAC3DAD426D0Q33699378-F2305B33-2FBE-4C15-8104-2C62F9B11290Q33755862-4F08C980-07B2-4E4E-B542-40E1D623E82CQ33822119-576B273D-6642-4BB2-B8D5-B1B5378CB9C8Q34372987-8ACADC98-0D3E-4B8C-A4E7-0140DB9EEA17Q34382777-8B45798B-CA46-4AE5-8CD3-B3504CEAE2A9Q34497045-BDD765F4-0646-45BD-9B4D-FE8F2099B5DDQ34540273-ACFB8F7F-1EBA-42BC-A6E0-74AD0A3CDE61Q34576062-28D8803F-566C-4A5A-B6A0-48578B7264B7Q34682072-0A6A4A76-5014-438B-95B9-BCFA1E974256Q34758583-12385848-9D0E-412B-B238-C441BE221A77Q34986178-4984A79C-714B-4C43-A5FD-9A525B3822C7Q34986188-050B6720-CDA4-491A-9A56-56C62936DFEEQ35093992-A143DA6D-4F35-4457-BC9B-E7ADE1D979BCQ35581006-27FE6823-DCF1-4C97-8599-5EE7B8C83FD8Q35679353-77B48DC8-1C28-4BAC-829A-5CD7A6E87DEBQ35822194-6DB0F6A5-BE03-4AC6-8722-936EB706CE8BQ35911227-D915D74B-31DE-4C53-A730-D03FC9881999Q35992132-BCE28354-9532-4067-BD07-FDBDBA5B2F8FQ36141097-EEB77C05-6197-40D1-8B2E-6FF9D03EB0FDQ36284645-1B52739D-F4A3-4D8A-BF04-E5DC8921560CQ36347314-84DB27E5-1789-4331-A17F-34E0298E1754Q36352100-BF73D62F-53CE-4D23-8FE0-DA44AC700062Q36473355-8D8F0F2E-74F4-4DB4-B6BA-CE93F2EE96E5Q36553517-A26C61F8-7986-4273-9BF5-1C8AA1932D8AQ36600294-7270E27C-8E41-40B0-90E6-6B0451A3CA2BQ36649565-4015B149-D0EC-457E-9F38-7EDFE98D47F5Q36817127-21B5CA99-1A33-431B-A82F-F6C6F86A9DC5
P2860
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
@ast
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
@en
type
label
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
@ast
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
@en
prefLabel
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
@ast
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
@en
P2093
P356
P1433
P1476
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
@en
P2093
James H Doroshow
Jeffrey Weber
Kim Margolin
Scott Christensen
Thomas Gajewski
Tim Synold
Tracey Baratta
P304
P356
10.1002/CNCR.21265
P407
P577
2005-09-01T00:00:00Z