GABAergic mechanism of propofol toxicity in immature neurons - Wikidata - awgldk - TriplyDB

GABAergic mechanism of propofol toxicity in immature neurons

GABAergic mechanism of propofol toxicity in immature neurons

http://www.wikidata.org/entity/Q33371492

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Molecular mechanisms of antiseizure drug activity at GABAA receptors Propofol anesthesia induces proapoptotic tumor necrosis factor-α and pro-nerve growth factor signaling and prosurvival Akt and XIAP expression in neonatal rat brain.Regional and temporal profiles of calpain and caspase-3 activities in postnatal rat brain following repeated propofol administration Propofol exposure in pregnant rats induces neurotoxicity and persistent learning deficit in the offspring Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons.Down-regulation of microRNA-21 is involved in the propofol-induced neurotoxicity observed in human stem cell-derived neurons Positron Emission Tomography with [(18)F]FLT Revealed Sevoflurane-Induced Inhibition of Neural Progenitor Cell Expansion in vivo.Are anaesthetics toxic to the brain?Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation.MicroRNAs: New Players in Anesthetic-Induced Developmental Neurotoxicity Propofol at clinically relevant concentrations increases neuronal differentiation but is not toxic to hippocampal neural precursor cells in vitro.Potential Adverse Effects of Prolonged Sevoflurane Exposure on Developing Monkey Brain: From Abnormal Lipid Metabolism to Neuronal Damage Propofol Suppressed Hypoxia/Reoxygenation-Induced Apoptosis in HBVSMC by Regulation of the Expression of Bcl-2, Bax, Caspase3, Kir6.1, and p-JNK Technical communication: stability of propofol in polystyrene-based tissue culture plates.Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway.Propofol compared with isoflurane inhibits mitochondrial metabolism in immature swine cerebral cortex.Role of mitochondrial complex I and protective effect of CoQ10 supplementation in propofol induced cytotoxicity.Neurocognitive Adverse Effects of Anesthesia in Adults and Children: Gaps in Knowledge.Recent Insights Into Molecular Mechanisms of Propofol-Induced Developmental Neurotoxicity: Implications for the Protective Strategies.Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature.Long-term action of propofol on cognitive function and hippocampal neuroapoptosis in neonatal rats.Caffeine combined with sedative/anesthetic drugs triggers widespread neuroapoptosis in a mouse model of prematurity.Propofol inhibits proliferation and induces neuroapoptosis of hippocampal neurons in vitro via downregulation of NF-κB p65 and Bcl-2 and upregulation of caspase-3.Effects of Propofol Treatment in Neural Progenitors Derived from Human-Induced Pluripotent Stem Cells.Propofol Exposure in Early Life Induced Developmental Impairments in the Mouse Cerebellum.Propofol Induces Apoptosis of Neurons but Not Astrocytes, Oligodendrocytes, or Neural Stem Cells in the Neonatal Mouse Hippocampus.Propofol-induced neurotoxicity in hESCs involved in activation of miR-206/PUMA signal pathway.Insufficient Astrocyte-Derived Brain-Derived Neurotrophic Factor Contributes to Propofol-Induced Neuron Death Through Akt/Glycogen Synthase Kinase 3β/Mitochondrial Fission Pathway.Propofol Affects Neurodegeneration and Neurogenesis by Regulation of Autophagy via Effects on Intracellular Calcium Homeostasis.The effects of general anaesthesia on memory in children: a comparison between propofol and sevoflurane.TNF-α Mediates the Intrinsic and Extrinsic Pathway in Propofol-Induced Neuronal Apoptosis Via PI3K/Akt Signaling Pathway in Rat Prefrontal Cortical Neurons.The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction : Mechanism for the effects of propofol on cognitive function.Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway Propofol Alters Long Non-Coding RNA Profiles in the Neonatal Mouse Hippocampus: Implication of Novel Mechanisms in Anesthetic-Induced Developmental Neurotoxicity

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P2860

GABAergic mechanism of propofol toxicity in immature neurons

http://www.wikidata.org/entity/Q33371492

description

2008 nî lūn-bûn

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2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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GABAergic mechanism of propofol toxicity in immature neurons

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GABAergic mechanism of propofol toxicity in immature neurons

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GABAergic mechanism of propofol toxicity in immature neurons

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GABAergic mechanism of propofol toxicity in immature neurons

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GABAergic mechanism of propofol toxicity in immature neurons

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Journal of Neurosurgical Anesthesiology

P1476

GABAergic mechanism of propofol toxicity in immature neurons

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P2093

Gary Fiskum

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Margaret M McCarthy

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Sibel Kahraman

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Susan L Zup

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P2860

NKCC1 transporter facilitates seizures in the developing brain

Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits.

Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways.

Propofol-induced calcium signalling and actin reorganization within breast carcinoma cells.

Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin.

GABA: an excitatory transmitter in early postnatal life.

Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury.

Binding of propofol to blood components: implications for pharmacokinetics and for pharmacodynamics.

A role for actin in aging and apoptosis.

Propofol suppresses macrophage functions and modulates mitochondrial membrane potential and cellular adenosine triphosphate synthesis.

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233-240

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20

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