A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
about
New insights and therapeutics for immune-mediated thrombocytopenia.New advances in the treatment of adult chronic immune thrombocytopenic purpura: role of thrombopoietin receptor-stimulating agents.Current treatment options for primary immune thrombocytopenia.Preliminary nonclinical toxicity, pharmacokinetics, and pharmacodynamics of ALXN4100TPO, a thrombopoietin receptor agonist, in CD2F1 mice.Overview on concepts and applications of Fab antibody fragments.Milestones in understanding platelet production: a historical overview.The pharmacology and clinical application of thrombopoietin receptor agonists.Expression and bioactivity of recombinant human serum albumin and dTMP fusion proteins in CHO cells.Treatment of 5 dogs with immune-mediated thrombocytopenia using RomiplostimProtein-protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information.Directed evolution of a three-finger neurotoxin by using cDNA display yields antagonists as well as agonists of interleukin-6 receptor signaling.A Novel Peptide Thrombopoietin Mimetic Designing and Optimization Using Computational Approach.Generation of inhibitory monoclonal antibodies targeting matrix metalloproteinase-14 by motif grafting and CDR optimization.High affinity anti-inorganic material antibody generation by integrating graft and evolution technologies: potential of antibodies as biointerface molecules.Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus.Development of a sandwich enzyme-linked immunosorbent assay for dTMP-GH fusion protein by rational immunogen selection.Rational and efficient preparation of a chimeric protein containing a tandem dimer of thrombopoietin mimetic peptide fused to human growth hormone in Escherichia coli.
P2860
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P2860
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
@ast
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
@en
type
label
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
@ast
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
@en
prefLabel
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
@ast
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
@en
P2093
P2860
P356
P1476
A rationally designed agonist antibody fragment that functionally mimics thrombopoietin
@en
P2093
Jeremy P Springhorn
Katherine S Bowdish
Krista Johnson
Lynette M Smith
Mark W Renshaw
Peter Calveley
Shana Frederickson
Yamin Shen
P2860
P304
14307-14312
P356
10.1073/PNAS.0602658103
P407
P577
2006-09-14T00:00:00Z