Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
about
‘Crystal lattice engineering,’ an approach to engineer protein crystal contacts by creating intermolecular symmetry: Crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucinesA rationally designed agonist antibody fragment that functionally mimics thrombopoietinBiology and chemistry of thrombopoietic agentsEltrombopag: the discovery of a second generation thrombopoietin-receptor agonist.The biology of thrombopoietin and thrombopoietin receptor agonists.Thrombopoietin from beginning to end.Thrombopoiesis-stimulating agents and myelodysplastic syndromes.Normal and pathological dynamics of platelets in humans.Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin.Identification of the residues in the extracellular domain of thrombopoietin receptor involved in the binding of thrombopoietin and a nuclear distribution protein (human NUDC).Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms.Mutagenesis of the crystal contact of acidic fibroblast growth factor.An insight into the thermodynamic characteristics of human thrombopoietin complexation with TN1 antibody.Grafting of thrombopoietin-mimetic peptides into cystine knot miniproteins yields high-affinity thrombopoietin antagonists and agonists.Structural basis of the broadly neutralizing anti-interferon-α antibody rontalizumab.Extracellular domain N-glycosylation controls human thrombopoietin receptor cell surface levels.Thrombopoietin mutation in congenital amegakaryocytic thrombocytopenia treatable with romiplostim.
P2860
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P2860
Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structure of the receptor-bind ...... neutralizing antibody fragment
@ast
Structure of the receptor-bind ...... neutralizing antibody fragment
@en
Structure of the receptor-bind ...... neutralizing antibody fragment
@nl
type
label
Structure of the receptor-bind ...... neutralizing antibody fragment
@ast
Structure of the receptor-bind ...... neutralizing antibody fragment
@en
Structure of the receptor-bind ...... neutralizing antibody fragment
@nl
prefLabel
Structure of the receptor-bind ...... neutralizing antibody fragment
@ast
Structure of the receptor-bind ...... neutralizing antibody fragment
@en
Structure of the receptor-bind ...... neutralizing antibody fragment
@nl
P2093
P2860
P356
P1476
Structure of the receptor-bind ...... neutralizing antibody fragment
@en
P2093
Atsushi Matsumoto
Hideki Shigematsu
Hiroshi Miyazaki
Hiroshi Watarai
Kinya Ogami
Masako Hirose
Michael D Feese
Ryota Kuroki
Takanori Muto
Takashi Kato
P2860
P304
P356
10.1073/PNAS.0308530100
P407
P577
2004-02-17T00:00:00Z