Overlapping binding site for the endogenous agonist, small-molecule agonists, and ago-allosteric modulators on the ghrelin receptor.
about
Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsIdentification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling biasSeven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Allosteric transition: a comparison of two modelsAllosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discoveryHeterodimerization with Its splice variant blocks the ghrelin receptor 1a in a non-signaling conformation: a study with a purified heterodimer assembled into lipid discs.Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor.Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential.MC4R dimerization in the paraventricular nucleus and GHSR/MC3R heterodimerization in the arcuate nucleus: is there relevance for body weight regulation?Ghrelin stimulates myogenic differentiation in a mouse muscle satellite cell line and in primary cultures of bovine myoblasts.Growth hormone secretagogues and growth hormone releasing peptides act as orthosteric super-agonists but not allosteric regulators for activation of the G protein Galpha(o1) by the Ghrelin receptor.Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β(2)-adrenergic receptorUnique interaction pattern for a functionally biased ghrelin receptor agonist.A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors.PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation.
P2860
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P2860
Overlapping binding site for the endogenous agonist, small-molecule agonists, and ago-allosteric modulators on the ghrelin receptor.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Overlapping binding site for t ...... ators on the ghrelin receptor.
@ast
Overlapping binding site for t ...... ators on the ghrelin receptor.
@en
type
label
Overlapping binding site for t ...... ators on the ghrelin receptor.
@ast
Overlapping binding site for t ...... ators on the ghrelin receptor.
@en
prefLabel
Overlapping binding site for t ...... ators on the ghrelin receptor.
@ast
Overlapping binding site for t ...... ators on the ghrelin receptor.
@en
P50
P356
P1476
Overlapping binding site for t ...... ators on the ghrelin receptor.
@en
P2093
Thomas M Frimurer
Tine Halkjaer
P356
10.1124/MOL.108.049189
P577
2008-10-15T00:00:00Z